内蒙古自治区2010-2020年头颈部肿瘤死亡趋势分析  

Analysis for the mortality trend of head and neck cancer in Inner Mongolia Autonomous Region from 2010 to 2020

作　　者：吴宜伟 韩静 颜雪 王文瑞[2] WU Yiwei;HAN Jing;YAN Xue;WANG Wenrui(School of Public Health,Baotou Medical College,Baotou 014040,China;Department of Chronic Disease Prevention and Control,Inner Mongolia Center for Disease Control and Prevention)

机构地区：[1]内蒙古科技大学包头医学院公共卫生学院,包头014040 [2]内蒙古自治区疾病预防控制中心(内蒙古自治区预防医学科学院)慢性病防治科

出　　处：《实用肿瘤学杂志》2025年第2期86-90,共5页Practical Oncology Journal

摘　　要：目的 分析2010—2020年内蒙古自治区肿瘤登记地区头颈部肿瘤(鼻咽癌、喉癌、甲状腺癌和口腔癌)的死亡情况及变化趋势,为内蒙古自治区头颈部肿瘤的防控工作提供科学依据。方法 对2010—2020年内蒙古自治区肿瘤登记数据库中头颈部肿瘤(鼻咽癌、喉癌、甲状腺癌和口腔癌)死亡数据进行整理,分性别、城乡和癌种计算头颈部肿瘤的中标死亡率;采用Joinpoint 4.9.1.0软件计算平均年度变化百分比(average annual percentage change, AAPC),分析头颈部肿瘤及分癌种的中标死亡率变化趋势。结果 内蒙古自治区肿瘤登记地区头颈部肿瘤中标死亡率为2.85/10万,男性中标死亡率(4.24/10万)高于女性(1.53/10万),农村地区中标死亡率(2.93/10万)高于城市地区(2.79/10万)。口腔癌中标死亡率最高为1.16/10万,鼻咽癌中标死亡率最低为0.42/10万。2010—2020年头颈部肿瘤中标死亡率以平均每年3.79%的幅度上升,变化趋势有统计学意义(95%CI:1.45%~6.17%,P=0.005),男性头颈部肿瘤中标死亡率以平均每年7.27%的幅度上升,变化趋势有统计学意义(95%CI:3.05%~11.65%,P=0.003);女性中标死亡率以平均每年-1.08%的幅度下降,变化趋势无统计学意义(95%CI:-4.51%~2.47%,P=0.500)。口腔癌中标死亡率呈现上升趋势(AAPC为7.35%,P=0.040),喉癌、甲状腺癌和鼻咽癌中标死亡率变化趋势无统计学意义(AAPC分别为为3.36%、1.38%和-0.36%,P>0.05)。结论 内蒙古自治区肿瘤登记地区2010—2020年头颈部肿瘤中标死亡率呈上升趋势,应重视头颈部肿瘤防治工作,以农村地区及男性群体为重点防控工作对象,针对职业暴露、饮酒等高危行为加强控制措施,重点关注口腔癌预防控制,强化HPV疫苗接种与烟草控制政策。Objective The objective of this study was to analyze the mortality and changing trend of head and neck cancer(nasopharyngeal cancer,laryngeal cancer,thyroid cancer,and oral cancer)in cancer registry areas of Inner Mongolia Autonomous Re-gion from 2010 to 2020,and to provide a scientific basis for the prevention and control of head and neck cancer in Inner Mongolia Au-tonomous Region.Methods The mortality data for head and neck cancers(nasopharyngeal cancer,laryngeal cancer,thyroid cancer,and oral cancers)in the tumor registration database of Inner Mongolia Autonomous Region from 2010 to 2020 were sorted out,and the China standard mortality of head and neck were calculated by gender,urban and rural areas,and cancer types.The average annual per-centage change(AAPC)was analyzed using Joinpoint 4.9.1.0 software to assess the trend of China standard mortality of head and neck cancers and cancer types.Results The China standard mortality of head and neck cancers in cancer registry areas of Inner Mongolia was 2.85/100,000.The China standard mortality of males(4.24/100,000)was higher than that of females(1.53/100,000),and the China standard mortality in rural areas(2.93/100,000)was higher than that in urban areas(2.79/100,000).The China standard mortality of oral cancer was the highest at 1.16/100,000,and the China standard mortality of nasopharyngeal cancer was the lowest at 0.42/100,000.From 2010 to 2020,the mortality of head and neck cancers increased by an average annual rate of 3.79%(95%CI:1.45%-6.17%),and the trend was statistically significant(P=0.005).The mortality of male head and neck canc-er increased by an annual rate of 7.27%(95%CI:3.05%-11.65%),and the trend was statistically significant(P=0.003).The mortality of females decreased by an average annual rate of 1.08%(95%CI:-4.51%-2.47%),and the trend was not statistically significant(P=0.500).The mortality of oral cancer showed an upward trend with an AAPC of 7.35%(P=0.040),and the mortality of laryngeal cancer,thyroid cancer and nasopharyngeal cancer showed

关 键 词：头颈部肿瘤 死亡率 趋势 肿瘤登记 内蒙古自治区 

分 类 号：R739.91[医药卫生—肿瘤]