乳腺腋窝淋巴结细针穿刺细胞学与组织病理学对照分析  

Comparative analysis of fine needle aspiration cytology and histopathology in axillary lymph nodes

作　　者：翟博雅 黄振东 周晋星 吴妍 席雷 王聪 张智弘 戎荣 Zhai Boya;Huang Zhendong;Zhou Jinxing;Wu Yan;Xi Lei;Wang Cong;Zhang Zhihong;Rong Rong(Department of Pathology,the First Affiliated Hospital with Nanjing Medical University/Jiangsu Province Hospital,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院/江苏省人民医院病理科,南京210029

出　　处：《临床与实验病理学杂志》2025年第4期469-473,共5页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的探讨超声引导下乳腺腋窝淋巴结细针穿刺细胞学检查(ultrasound guided-fine needle aspiration cytology,US-FNAC)在乳腺癌诊断中的作用。方法选取203例乳腺癌患者的腋窝淋巴结细针穿刺细胞学检查(fine needle aspiration cytology,FNAC)样本,采用沉降式液基细胞学技术制片,以新辅助治疗后组织病理学结果为金标准,对照FNAC样本的诊断符合率。结果203例腋窝淋巴结FNAC样本中,111例诊断为阳性,38例诊断为可疑阳性,54例诊断为阴性,以术后病理结果为金标准,FNAC诊断的准确性为85.2%,敏感性为98.0%,特异性为90.0%。结论FNAC在诊断腋窝淋巴结是否存在转移方面具有较高的敏感性和准确性,而对于临床及影像怀疑淋巴结转移但FNAC阴性的患者,推荐进行前哨淋巴结活检。Purpose To investigate the role of ultrasound-guided fine needle aspiration cytology(US-FNAC)in the diagnosis of breast cancer.Methods Fine needle aspiration cytology(FNAC)samples of 203 patients with breast cancer were selected and prepared by liquid-based cytology.The results of histopathology after neoadjuvant therapy were used as the gold standard to compare with the diagnostic results of FNAC samples,and then evaluated the diagnostic coincidence rate of FNAC samples.Results Of 203 axillary lymph node FNAC samples,111 cases were diagnosed as positive,38 cases were diagnosed as suspicious for positivity,and 54 cases were diagnosed as negative.The diagnostic accuracy of FNAC was 85.2%,the sensitivity of FNAC was 98.0%,and the specificity of FNAC was 90.0%.Conclusion FNAC has high sensitivity and accuracy in the diagnosis of axillary lymph node metastasis.Sentinel lymph node biopsy is recommended for patients with negative FNAC but clinically and radiographically suspected lymph node metastasis.

关 键 词：乳腺肿瘤 细针穿刺细胞学 细胞学 新辅助治疗 

分 类 号：R737.9[医药卫生—肿瘤]