新型污染物6PPD/6PPD-Q的转化、毒性效应与风险控制  

Research Progress on Transformation,Toxicity Effects and Risk Control of Emerging Pollutants 6PPD/6PPD-Q

作　　者：梅易豪 米热扎提江·喀由木 段桂兰[2,3] MEI Yihao;Mirezhatijiang KAYOUMU;DUAN Guilan(Henan Institute of Advanced Technology,Zhengzhou University,Zhengzhou 450000,China;Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China;University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]郑州大学河南先进技术研究院,郑州450000 [2]中国科学院生态环境研究中心,北京100085 [3]中国科学院大学,北京100049

出　　处：《生态毒理学报》2025年第2期310-327,共18页Asian Journal of Ecotoxicology

基　　金：国家自然科学基金资助项目(41991332)。

摘　　要：轮胎磨损颗粒化合物N-(1,3-二甲基丁基)-N’-苯基对苯二胺(6PPD)及其衍生物6PPD醌(6PPD-Q)已成为日益引起关注的新污染物。由于橡胶相关产品的大规模生产和广泛使用,6PPD和6PPD-Q已被确定在环境基质中普遍存在,具有生物毒性和生态健康风险,并可通过多种暴露途径进入人体从而对健康构成威胁。复杂的环境因素如温度、光照、臭氧浓度、水文条件以及生物作用等会对境介质中6PPD/6PPD-Q的浓度、分布及转化产生影响,且6PPD/6PPD-Q易与其他污染物产生交互作用从而影响其环境行为。本文综述了6PPD及其氧化产物6PPD-Q在环境中的污染特征,总结了其在大气、土壤和水体中的转化机制,如光解与微生物还原等,并重点阐述了6PPD/6PPD-Q的生态毒性与健康风险。在此基础上提出了控制此类新污染物的环境风险管理技术,并对未来研究方向进行了展望,以期为进一步开展6PPD/6PPD-Q的生物毒性效应、机制研究和健康风险评估提供科学线索和参考。Tire wear particle compound N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine(6PPD)and its derivative 6PPD quinone(6PPD-Q)have become emerging pollutants that attract increasing attention.Due to the large-scale production and wide use of rubber-related products,6PPD and its oxidation product 6PPD-Q have been identified as ubiquitous in environmental matrices,with biological toxicity and ecological risks.The pollutants 6PPD/6PPD-Q can enter the human body through a variety of exposure routes,thereby posing great threats to the health of mankind.Complex environmental factors,such as temperature,light,ozone concentration,hydrological conditions and biological effects,influence the concentration,distribution and transformation of 6PPD/6PPD-Q in various environments.Specifically,6PPD/6PPD-Q ubiquitously interact with other environmental contaminants d uring the processes of migration and transformation,which influence their environmental behavior.In this paper,the pollution characteristics of 6PPD and 6PPD-Q in the environments were reviewed,and the transformation mechanisms of 6PPD/6PPD-Q in the atmosphere,soil and water were summarized,such as photolysis and m icrobial reduction.Furthermore,the ecotoxicity and health risks of 6PPD/6PPD-Q were emphasized.Furthermore,the strategies for controlling the environmental risk of these emerging pollutants were proposed,and future research aspects were also prospected.This review will provide scientific clues and references for further researches on the biological toxicological effects,transformation mechanisms,and health risk assessment of 6PPD and 6PPD-Q.

关 键 词：6PPD 6PPD-Q 污染特征 转化机制 风险控制 

分 类 号：X171.5[环境科学与工程—环境科学]