屎肠球菌后生元对育成期母貂生长性能、养分表观消化率和肠道健康的影响  

Effects of Enterococcus faecium Postibiotics on Growth Performance,Nutrient Apparent Digestibility and Intestinal Health of Growing Female Minks

作　　者：曹林 孙逢雪 陈健 蒋子怡 王光[1] 王利华[1] CAO Lin;SUN Fengxue;CHEN Jian;JIANG Ziyi;WANG Guang;WANG Lihua(College of Animal Science and Technology,Qingdao Agricultural University,Qingdao 266109,China)

机构地区：[1]青岛农业大学动物科技学院,青岛266109

出　　处：《动物营养学报》2025年第4期2638-2647,共10页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：山东省现代农业特种经济动物产业技术体系(SDAIT-21)。

摘　　要：本试验旨在研究饲粮中添加屎肠球菌后生元对育成期母貂生长性能、养分表观消化率、抗氧化能力、免疫功能和肠道菌群的影响。选取12周龄白色母貂120只,随机分成4个组,每组15个重复,每个重复2只。4组饲粮中屎肠球菌后生元的添加水平分别为0(对照组)、0.05%(0.05%PEF组)、0.10%(0.10%PEF组)、0.15%(0.15%PEF组)。预试期1周,正试期7周。结果表明:1)与对照组相比,0.05%PEF组、0.10%PEF组和0.15%PEF组的末重和平均日增重显著增加(P<0.05),料重比显著降低(P<0.05)。2)与对照组相比,0.10%PEF组的干物质和粗蛋白质表观消化率显著增加(P<0.05)。3)与对照组相比,0.10%PEF组的空肠黏膜总抗氧化能力显著增加(P<0.05),0.05%PEF组和0.15%PEF组的空肠黏膜谷胱甘肽过氧化物酶活性显著增加(P<0.05)。4)与对照组相比,0.05%PEF组、0.10%PEF组和0.15%PEF组的空肠黏膜白细胞介素-8含量显著降低(P<0.05);0.10%PEF组的空肠黏膜肿瘤坏死因子-α含量显著降低(P<0.05),空肠黏膜分泌型免疫球蛋白A含量显著增加(P<0.05);0.10%PEF组和0.15%PEF组的空肠黏膜白细胞介素-10含量显著增加(P<0.05)。5)与对照组相比,0.10%PEF组的Ace指数、Chao指数和Sobs指数显著升高(P<0.05),0.05%PEF组的肠道葡萄球菌属和不动杆菌属相对丰度显著升高(P<0.05)。由此可见,饲粮中添加屎肠球菌后生元能够提高育成期母貂的生长性能和养分表观消化率,改善机体免疫功能和抗氧化能力,提高肠道菌群多样性。本试验条件下,饲粮中屎肠球菌后生元的适宜添加水平为0.10%。This experiment was conducted to investigate the effects of Enterococcus faecium postbiotics on growth performance,nutrient apparent digestibility,antioxidant capacity,immune function and intestinal microbiota of growing female minks.A total of 120 healthy white female minks at 12 weeks of age were randomly divided into 4 groups with 15 replicates in each group and 2 minks in each replicate.Minks in the 4 groups were fed the basal diets supplemented with 0(control group),0.05%(0.05%PEF group),0.10%(0.10%PEF group)and 0.15%(0.15%PEF group)Enterococcus faecium postbiotics,respectively.The experiment lasted for 7 weeks after 1 week adaptation period.The results showed as follows:1)compared with the control group,the final body weight and average daily gain of 0.05%PEF group,0.10%PEF group and 0.15%PEF group were significantly increased(P<0.05),and ratio of feed to gain was significantly decreased(P<0.05).2)Compared with the control group,the dry matter and crude protein apparent digestibility of 0.10%PEF group were significantly increased(P<0.05).3)Compared with the control group,the jejunal mucosa total antioxidant capacity 0.10%PEF group was significantly increased(P<0.05),the jejunal mucosa glutathione peroxidase activity of 0.05%PEF group and 0.15%PEF group was significantly increased(P<0.05).4)Compared with the control group,the jejunal mucosa interleukin-8 content of 0.05%PEF group,0.10%PEF group and 0.15%PEF group was significantly decreased(P<0.05);the jejunal mucosa tumor necrosis factor-α content of 0.10%PEF group was significantly decreased(P<0.05),and the jejunal mucosa secretory immunoglobulin A content was significantly increased(P<0.05);the jejunal mucosa interleukin-10 content of 0.10%PEF group and 0.15%PEF group was significantly increased(P<0.05).5)Compared with the control group,the Ace index,Chao index and Sobs index of 0.10%PEF group were significantly increased(P<0.05),and the relative abundances of Staphylococcus and Acinetobacter in intestine of 0.05%PEF group were significantly increased(P<

关 键 词：屎肠球菌 后生元 生长性能 养分表观消化率 抗氧化能力 免疫功能 肠道菌群 

分 类 号：S816.7[农业科学—饲料科学]