肺癌非肿瘤致死性疾病的研究与分析  

Study and analysis of non-tumor fatal diseases of lung cancer

作　　者：唐浩威 李和权[1] TANG Hao-wei;LI He-quan(Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 310000,China)

机构地区：[1]浙江大学医学院附属第一医院呼吸与危重症医学科,310000 [2]宁波市奉化区人民医院呼吸与危重症医学科,315500

出　　处：《中国现代药物应用》2025年第7期40-44,共5页Chinese Journal of Modern Drug Application

基　　金：国家自然科学基金(项目编号:81970015)。

摘　　要：目的探讨肺癌非肿瘤致死性疾病构成及特点。方法收集因非肿瘤疾病死亡的肺癌患者病案资料,分析患者的死因种类及构成比、不同死因各年龄段人次及构成比、不同死因各肿瘤分期的人次及构成比。结果共纳入204例符合标准的死亡患者资料,肺炎、间质性肺病、心力衰竭、肺栓塞居死因的前4位,合计占84.80%。肺炎致死发生最多,占33.82%,其次为间质性肺病,占22.06%,心力衰竭占18.63%,肺栓塞占10.29%。肺炎、间质性肺病、心力衰竭、肺栓塞死亡人次主要集中在Ⅳ期肺癌,其中肺炎占69.57%,间质性肺病占57.78%,心力衰竭占78.95%,肺栓塞占80.95%。其他疾病如营养不良、急性心肌梗死、粒细胞缺乏、急性脑梗死、消化道出血、急性肾衰竭死亡人次也主要集中在Ⅳ期肺癌。肺炎、间质性肺病、心力衰竭、肺栓塞死亡人次主要集中在61~80岁年龄段,其中肺炎占68.12%,间质性肺病占84.44%,心力衰竭占60.53%,肺栓塞占71.43%。结论肺炎、间质性肺病、心力衰竭、肺栓塞构成肺癌非肿瘤致死性疾病的主要病种,医院应根据死因谱特点加强肺癌患者并发疾病的诊治,尤其需重点关注肺炎、间质性肺病、心力衰竭、肺栓塞的防治,以达到延长肺癌患者的生存周期和提高生活质量的目的。Objective To explore the composition and characteristics of non-tumor fatal diseases of lung cancer.Methods The medical records of patients with lung cancer who died from non-tumor diseases were collected,and the types and composition ratios of causes of death,the number and composition ratios of different causes of death in different age groups,and the number and composition ratios of different causes of death and tumor stages were analyzed.Results A total of 204 eligible deaths were included,with pneumonia,interstitial lung disease,heart failure,and pulmonary embolism ranking among the top 4 causes of death,accounting for a total of 84.80%.Pneumonia was the most common cause of death(33.82%),followed by interstitial lung disease(22.06%),heart failure(18.63%)and pulmonary embolism(10.29%).The deaths of pneumonia,interstitial lung disease,heart failure and pulmonary embolism were mainly concentrated in stageⅣlung cancer,among which pneumonia accounted for 69.57%,interstitial lung disease accounted for 57.78%,heart failure accounted for 78.95%and pulmonary embolism accounted for 80.95%.Other diseases such as malnutrition,acute myocardial infarction,agranulocytosis,acute cerebral infarction,gastrointestinal bleeding,acute renal failure deaths were also mainly concentrated in stageⅣlung cancer.The deaths of pneumonia,interstitial lung disease,heart failure and pulmonary embolism were mainly concentrated in the age group of 61-80 years,among which pneumonia accounted for 68.12%,interstitial lung disease accounted for 84.44%,heart failure accounted for 60.53%and pulmonary embolism accounted for 71.43%.Conclusion Pneumonia,interstitial lung disease,heart failure and pulmonary embolism constitute the main non-tumor fatal diseases of lung cancer.Hospitals should strengthen the diagnosis and treatment of concurrent diseases of lung cancer patients according to the characteristics of the spectrum of causes of death,especially the prevention and treatment of pneumonia,interstitial lung disease,heart failure and pulmonar

关 键 词：非肿瘤致死性疾病 肺癌 肿瘤分期 

分 类 号：R734.2[医药卫生—肿瘤]