静电纺羧甲基纤维素伤口敷料的研究进展  

Research progress of wound dressing for electrospinning carboxymethyl cellulose

作　　者：李明聪 陈文静[1] 孙明楷 牛世杰 陶苗苗 周蓉[1] LI Mingcong;CHEN Wenjing;SUN Mingkai;NIU Shijie;TAO Miaomiao;ZHOU Rong(Qingdao University,Qingdao,266071,China;Qingdao Textile Inspection Co.,Ltd.,Qingdao,266001,China)

机构地区：[1]青岛大学,山东青岛266071 [2]青岛纺检检验有限公司,山东青岛266001

出　　处：《棉纺织技术》2025年第5期68-73,共6页Cotton Textile Technology

基　　金：教育部“产学合作协同育人”项目(231106429200559);中国纺织工业联合会项目(2021BKJGLX763);中国高教学会重点课题(24RH0309)。

摘　　要：总结静电纺羧甲基纤维素(CMC)伤口敷料的研究进展。介绍了不同方法制备的CMC伤口敷料的特点,包括CMC水凝胶、CMC膜和CMC非织造布。重点梳理了基于静电纺丝技术的CMC伤口敷料的制备技术、结构设计和功能化及生物性能研究。认为:静电纺CMC生物纳米纤维毡具备对伤口渗出液的高吸收和凝胶化止血功能,其特殊结构可作为多种药物的递送载体,促进伤口愈合和皮肤修复,但细胞毒性试验、动物试验尚在探索中,材料的性能参数及评价体系尚不完善,仍有许多问题亟待解决。The research progress of wound dressing for electrospinning carboxymethyl cellulose(CMC)was summarized.The characteristics of CMC wound dressing preparation by different methods,including CMC hydrogel,CMC membrane and CMC nonwovens,were introduced.The preparation technology,structural design,functionalization and biological property of CMC wound dressing based on electrospinning technology were reviewed.It is considered that CMC bio-nano fiber felt has the function of high absorption and gelation of wound exudate and hemostasis,its special structure can be used as a delivery carrier of various drugs to promote wound healing and skin repair,but the cytotoxicity test and animal test are still being explored,the performance parameters and evaluation system of the material are not perfect,there are still many problems need to be solved.

关 键 词：静电纺丝 羧甲基纤维素 纳米纤维 凝胶化 伤口敷料 抗菌性 

分 类 号：TS102.1[轻工技术与工程—纺织工程]