环境和食品样品中药物及个人护理品的污染现状及样品前处理分析技术  

Current status of contamination of environmental and food samples with pharmaceutical and personal care products and sample pretreatment analytical techniques

作　　者：马金燕 赵汝松 MA Jinyan;ZHAO Rusong(Boxing County Ecological and Environmental Monitoring Center,Binzhou 256500,China;Shandong Analysis and Test Center,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250014,China)

机构地区：[1]博兴县生态环境监控中心,山东滨州256500 [2]齐鲁工业大学(山东省科学院)山东省分析测试中心,山东济南250014

出　　处：《山东科学》2025年第2期28-40,共13页Shandong Science

基　　金：泰山学者人才工程项目(ts20190948);山东省企业技术创新项目(2024537010000879、2024537020000144)。

摘　　要：药物及个人护理品(PPCPs)残留作为一类新兴有机污染物,其组分具有内分泌干扰性、伪持久性及生态毒性。鉴于其在医疗、畜牧及化妆品等行业的广泛应用,近年来,PPCPs在地表水、地下水、工业污泥乃至牛奶等食品中被频繁检出,引发人们对其安全性的高度关注。然而,由于PPCPs在实际样品中残留浓度极低,且存在复杂的基质效应,其直接定量分析面临诸多困难。因此,在进行仪器分析前,需借助行之有效的样品前处理方法对PPCPs进行富集分析。首先系统介绍了PPCPs的危害与污染现状,并对双酚和非甾体抗炎药这两种典型PPCPs的污染情况展开详细说明。其次列举了几种样品前处理技术,结合新型吸附剂材料,展示其在PPCPs分析检测中的应用,同时探讨新型吸附材料的发展趋势。最后总结PPCPs在分析检测过程中可能遇到的障碍和挑战。∶Residues of pharmaceuticals and personal care products(PPCPs)are an emerging class of organic contaminants known for their endocrine-disrupting properties,pseudo-persistence,and ecotoxicity.Because of their wide application in the medical,animal husbandry,and cosmetic industries,PPCPs have been frequently detected in surface water,groundwater,industrial sludge,and even food such as milk in recent years,raising significant concerns about their safety.However,because PPCPs are present at very low concentrations in real samples and are affected by complex matrix effects,direct quantitative analysis is challenging.Therefore,before instrumental analysis,effective sample pretreatment methods are required for the enrichment analysis of PPCPs.In recent years,many novel materials have been developed for the extraction of trace contaminants.First,this paper provides a systematic introduction to the hazards and contamination status of PPCPs,followed by a detailed discussion of the contamination of two typical PPCPs:bisphenols and nonsteroidal anti-inflammatory drugs.Second,it lists several sample pretreatment techniques,highlighting the application of novel adsorbent materials in PPCP analysis and detection,while also exploring the development trends of these new adsorbent materials.Finally,the paper summarizes the obstacles and challenges that may be encountered in the analysis and detection of PPCPs.

关 键 词：药物及个人护理品 新污染物 样品前处理 新型吸附剂 

分 类 号：X171[环境科学与工程—环境科学]