肠道微生态与子宫内膜癌发生发展相关性的研究进展  

Correlation of intestinal microecology with endometrial carcinoma development:research progress

作　　者：彭皓晨 邵亚雯 王剑[2] 毛宝宏[2] 李娟[2] 曹晓翠 吴珍珍 PENG Haochen;SHAO Yawen;WANG Jian;MAO Baohong;LI Juan;CAO Xiaocui;WU Zhenzhen(The First School of Clinical Medical,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;不详)

机构地区：[1]甘肃中医药大学第一临床医学院,甘肃兰州730000 [2]甘肃省妇幼保健院

出　　处：《中国微生态学杂志》2025年第3期350-353,共4页Chinese Journal of Microecology

基　　金：甘肃省自然科学基金(22JR5RA718)。

摘　　要：子宫内膜癌是女性常见的恶性肿瘤之一,发病率呈逐年上升趋势,其发生的危险因素多与脂质、激素等代谢紊乱和免疫失衡有关。肠道微生态作为存在着庞大微生物种群的内生态环境,参与多种代谢途径和免疫调节。近年来肠道微生态的研究已成为临床防治的前沿科学,肠道微生物组成改变和肠道内环境失衡在多种恶性肿瘤发生发展中的作用为探索子宫内膜癌与肠道微生态的相关性研究提供了良好的基础。本文就肠道微生态紊乱对子宫内膜癌发生发展机制的影响作一综述。Endometrial carcinoma is one of the common malignant tumors in women,and the incidence rate is increasing year by year.The risk factors for its development are mostly related to metabolic disorders such as the imbalance of lipids,hormones and immune.Gut microbiota,as an internal ecological environment with a large microbial population,is involved in multiple metabolic pathways and immune regulation.In recent years,the study on intestinal microecology has become a cutting-edge science for clinical prevention and treatment,and the role of altered intestinal microbial composition and imbalance of intestinal internal environment in the development of various malignant tumors provides a good foundation for exploring the correlation between endometrial carcinoma and intestinal microecology.This article provides an overview on the impacts of intestinal microecological disorders on the mechanisms of endometrial carcinoma occurrence and development.

关 键 词：肠道微生态 子宫内膜癌 肠道菌群 炎症 代谢 

分 类 号：R737.33[医药卫生—肿瘤]