毛发中毒(药)物分析概述及相关研究进展  

Overview and Related Research Progress of Poison (Medicine) Analysis in Hair

作　　者：王愿皓 李纪彬[1] 吴德岸 WANG Yuanhao;LI Jibin;WU De′an(Zhongshan Public Security Bureau Torch Development Zone Branch,Zhongshan 528400,China)

机构地区：[1]中山市公安局开发区分局,广东中山528400

出　　处：《山东化工》2025年第7期145-148,共4页Shandong Chemical Industry

摘　　要：目前,人类毛发中毒(药)物分析已在法医毒物学、临床毒理学、环境污染以及农药残留监测等领域得到广泛应用并显示出独特的实践价值。毛发本质上是一种蛋白质纤维,主要通过角蛋白(二硫键、肽键)、黑色素等活性基团与有机毒(药)物分子发生化学键合或以范氏力相互作用,实现对毒(药)物的沉积与固定。本文综述了毛发分析的理论基础和毛发中毒(药)物的分析方法,为涉及毛发中毒(药)物分析应用的各个领域研究提供参考价值。The analysis of poisons(drugs)in human hair has been widely used in the fields of forensic toxicology,clinical toxicology,environmental pollution,and pesticide residue monitoring.Show unique practical value.As a solid biological specimen,hair is essentially a protein fiber,which is chemically bonded to organic poison(drug)molecules through keratin(disulfide bonds,peptide bonds),melanin and other active groups or in the form of Fan's Force interaction to achieve deposition and fixation.This article summarizes the theoretical basis of hair analysis and the analysis method of poison(medicine)in hair,which provides reference value for various areas involving poison(medicine)analysis in hair applications.

关 键 词：毛发分析 生物检材 仪器分析 研究进展 

分 类 号：O657[理学—分析化学]