原发性女性生殖系统非霍奇金淋巴瘤两例并文献复习  

Primary Non-Hodgkin Lymphoma in the Female Genital System:Report of Two Cases and Review of the Literature

作　　者：张天宇 秦丽 曹冬焱 杨佳欣 刘毅 王涛[1] ZHANG Tianyu;QIN Li;CAO Dongyan;YANG Jiaxin;LIU Yi;WANG Tao(National Clinical Research Center for Obstetrics and Gynecology,Department of Obstetrics and Gynecology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China;Department of Obstetrics and Gynecology,The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture,Enshi,Hubei 445000,China)

机构地区：[1]中国医学科学院、北京协和医学院、北京协和医院妇产科、国家妇产疾病临床医学研究中心,北京100730 [2]恩施土家族苗族自治州中心医院妇产科,湖北恩施445000

出　　处：《中国医学科学院学报》2025年第2期314-318,共5页Acta Academiae Medicinae Sinicae

基　　金：北京协和医院中央高水平医院临床科研专项(2022-PUMCH-B-083);中国医学科学院医学与健康科技创新工程项目临床与转化医学研究专项(2022-I2M-C&T-B-023)。

摘　　要：原发性女性生殖系统淋巴瘤(PFGSL)是较为罕见的结外淋巴瘤,患者常首诊于妇科,目前诊治缺乏统一规范。2016年世界卫生组织造血与淋巴组织肿瘤分类对淋巴瘤的分类进行了更新,但未针对PFGSL进行详细阐述。绝大多数PFGSL为非霍奇金淋巴瘤,发病较常见于卵巢和宫颈,另有子宫体、阴道及外阴等罕见部位的个案报道。本文报道的2例女性生殖系统非霍奇金淋巴瘤分别来源于子宫体和卵巢,通过总结患者的诊治经过并进行文献复习,为临床医师对罕见病的识别及诊治提供借鉴。Primary female genital system lymphoma(PFGSL)is a rare subtype of extranodal lymphoma and patients commonly present in the department of gynecology.At present,there is a lack of uniform standards for the treatment of PFGSL.Although the classification of lymphoid neoplasmas was updated by the World Health Organization classification of haematolymphoid tumors in 2016,PFGSL was still not elaborated in sufficient detail.Most cases of PFGSL are non-Hodgkin lymphoma,involving the ovary and cervix.In some cases,involvement of uterine corpus,vagina,and vulva is reported.In this article,we report two cases of non-Hodgkin lymphoma in the female genital system,one from the uterus and the other from the ovary.By presenting the diagnosis and treatment of the two cases and reviewing the literature,we aim to provide a reference for clinicians in recognizing and treating rare cases.

关 键 词：女性生殖系统 非霍奇金淋巴瘤 治疗 预后 

分 类 号：R737[医药卫生—肿瘤]