壳聚糖/氧化石墨烯复合材料研究现状  

Research status of chitosan/graphene oxide composites

作　　者：莫丽娟 刘莹[2] 张靖羚 王子豪 MO Lijuan;LIU Ying;ZHANG Jingling;WANG Zihao(College of Materials Science and Engineering,Liaoning Technical University,Fuxin 123000,China;College of Science,Liaoning Technical University,Fuxin 123000,China)

机构地区：[1]辽宁工程技术大学材料科学与工程学院,阜新123000 [2]辽宁工程技术大学理学院,阜新123000

出　　处：《复合材料学报》2025年第3期1261-1271,共11页Acta Materiae Compositae Sinica

摘　　要：壳聚糖(CS)是具有良好生物相容性、可生物降解、无毒、抗菌等优点的天然碱性多糖,但CS材料力学性能较差、遇水易水解。氧化石墨烯(GO)具有较大的比表面积和良好的生物相容性、稳定性,能与其他材料结合制备出性能更优异的复合材料。将CS与GO进行复合,实现优势互补,可以得到兼具优异力学性能、生物活性和生物相容性的壳聚糖/氧化石墨烯(CS/GO)复合材料,CS/GO复合材料可以制备成水凝胶、纳米颗粒、薄膜、多孔材料等形式,这使CS/GO复合材料在环保、食品、医用等领域具有良好的应用前景。本文综述了CS/GO复合材料在药物载体、伤口敷料、组织工程支架、污染物吸附、食品保鲜5个方面的研究现状,并对CS/GO复合材料未来研究方向进行展望。Chitosan(CS)is a natural alkaline polysaccharide with good biocompatibility,biodegradable,non-toxic,antibacterial and other advantages,but CS material has poor mechanical properties and easy hydrolysis in water.Graphene oxide(GO)has a large specific surface area and good biocompatibility,stability,and can be combined with other materials to prepare more excellent properties of composite materials.By combining CS and GO to achieve complementary advantages,chitosan/graphene oxide(CS/GO)composites with excellent mechanical properties,biological activity and biocompatibility can be obtained,CS/GO composites can be prepared into hydrogels,nanoparticles,films,porous materials and other forms,which makes CS/GO composites have good application prospects in environmental protection,food,medical and other fields.In this paper,the research status of CS/GO composites in drug carrier,wound dressing,tissue engineering scaffold,contaminant adsorption,food preservation was reviewed,and the future research direction of CS/GO composites was prospected.

关 键 词：壳聚糖 氧化石墨烯 药物载体 伤口敷料 组织工程支架 吸附 食品保鲜 

分 类 号：R318.08[医药卫生—生物医学工程] TB332[医药卫生—基础医学]