西帕依固龈液联合西吡氯铵含漱液在牙龈炎治疗中的效果评估  

Evaluation of the efficacy of Xipayi gum-strengthening solution combined with cetylpyridinium chloride gargle in the treatment of gingivitis

作　　者：张佩佩 方厅洁 ZHANG Peipei;FANG Tingjie(Department of Stomatology,Putuo District People's Hospital,Zhoushan 316100,China)

机构地区：[1]舟山市普陀区人民医院口腔科,浙江舟山316100

出　　处：《全科医学临床与教育》2025年第4期334-337,共4页Clinical Education of General Practice

摘　　要：目的探究西帕依固龈液联合西吡氯铵含漱液治疗牙龈炎的临床疗效,分析对患者牙周状态、口腔健康影响程度量表(OHIP-14)评分的影响。方法选取就诊的100例牙龈炎患者为研究对象,按照治疗方案不同将患者分为观察组(n=49)和对照组(n=51)。在基础治疗的基础上,对照组予以西吡氯铵含漱液治疗,观察组予以西帕依固龈液联合西吡氯铵含漱液治疗,均持续治疗1个月。比较两组治疗总有效率,治疗前后牙周状态、OHIP-14评分,并记录治疗期间药物不良反应。结果观察组患者治疗总有效率为91.84%,高于对照组76.47%,差异有统计学意义(χ^(2)=4.39,P<0.05)。治疗后,观察组患者的牙龈指数(GI)、龈沟出血指数(SBI)和菌斑指数(PLI)均低于对照组,差异均有统计学意义(t分别=4.97、6.45、2.54,P均<0.05)。治疗后,观察组患者OHIP-14量表中的功能限制、生理疼痛、生理障碍、残障维度评分及OHIP-14总分均低于对照组,差异均有统计学意义(t分别=2.70、2.84、2.56、2.18、3.16,P均<0.05),两组不良反应发生率比较,差异无统计学意义(χ^(2)=0.16,P>0.05)。结论西帕依固龈液联合西吡氯铵含漱液治疗牙龈炎安全有效,能够有效改善患者牙周状态,促进患者口腔健康,安全性良好。Objective To investigate the clinical efficacy of Xipayi gum-strengthening solution combined with cetylpyridinium chloride gargle in the treatment of gingivitis,and analyze its impact on patients'periodontal status and oral health impact profile-14(OHIP-14)scores.Methods A total of 100 patients with gingivitis were selected as the study subjects and divided into an observation group(n=49)and a control group(n=51)according to different treatment regimens.Both groups received basic treatment,the control group treated with cetylpyridinium chloride gargle and the observation group treated with Xipayi gum-strengthening solution combined with cetylpyridinium chloride gargle.The treatment course was 1 month.The total effective rate,periodontal status,OHIP-14 scores before and after treatment,and adverse drug reactions during treatment were compared between the two groups.Results The total effective rate in the observation group was 91.84%,which was significantly higher than that in the control group(76.47%),the difference was statistically significant(χ^(2)=4.39,P<0.05).After treatment,the gingival index(GI),sulcus bleeding index(SBI),and plaque index(PLI)in the observation group were lower than those in the control group,the differences were statistically significant(t=4.97,6.45,2.54,P<0.05).After treatment,the functional limitation,physical pain,psychological discomfort,disability dimensions,and the total OHIP-14 score in the observation group were lower than those in the control group,the differences were statistically significant(t=2.70,2.84,2.56,2.18,3.16,P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(χ^(2)=0.16,P>0.05).Conclusion It is safe and effective to treat gingivitis with Xipayi gum-strengthening solution combined with cetylpyridinium chloride gargle,which can effectively improve patients'periodontal status and promote patients'oral health with good safety.

关 键 词：牙龈炎 西帕依固龈液 西吡氯铵含漱液 牙周指数 口腔健康影响程度量表评分 

分 类 号：R781.4[医药卫生—口腔医学]