早期康复运动干预对改善脑梗死偏瘫患者肌力与运动及生命质量的影响  

Effect of Early Rehabilitation Exercise Intervention on Improving Muscle Strength,Exercise and Quality of Life in Patients with Cerebral Infarction Hemiplegia

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作  者:黄鑫 HUANG Xin(The First People's Hospital of Jiujiang City,Jiujiang 332000,China)

机构地区:[1]九江市第一人民医院,江西九江332000

出  处:《中国药物经济学》2025年第3期119-124,共6页China Journal of Pharmaceutical Economics

摘  要:目的探讨早期康复运动干预对改善脑梗死偏瘫患者肌力、运动及生命质量的影响。方法选取2022年9月至2024年9月九江市第一人民医院收治的90例脑梗死偏瘫患者,随机分为对照组(45例)与观察组(45例)。对照组予以常规措施干预,观察组在对照组基础上实施早期康复运动干预。比较两组患者临床疗效、肌力分级、血清指标、生命质量、平衡效能、脑血流动力学、内皮功能及综合功能。结果观察组治疗总有效率(95.56%)高于对照组(77.78%),肌力优良率(68.89%)高于对照组(28.89%),差异有统计学意义(P<0.05);干预后观察组血清白蛋白(Alb)、血红蛋白(HGB)、淋巴细胞(LYM)、纤维蛋白原(FIB)低于对照组(P<0.05);干预后观察组生活质量综合评定问卷-74(GQOL-74)各维度评分高于对照组(P<0.05);干预后观察组修正版跌倒效能量表(MFES)评分、Berg平衡量表(BBS)评分高于对照组,起立-行走计时测试(TUGT)时间短于对照组,差异有统计学意义(P<0.05);干预后观察组阻力指数(RI)、搏动指数(PI)低于对照组,平均血流速度(Vm)高于对照组,差异有统计学意义(P<0.05);干预后观察组外周血内皮祖细胞(EPCs)、内皮型一氧化氮合酶(e NOS)高于对照组,内皮素1(ET-1)、血管性血友病因子(vWF)低于对照组,差异有统计学意义(P<0.05);干预后,观察组Fugl-Meyer运动功能评分量表(FMA)评分、蒙特利尔认知评估量表(MoCA)评分、汉语失语症检查评分、日常生活能力量表(ADL)评分高于对照组,美国国立卫生研究院脑卒中量表(NIHSS)评分低于对照组,差异有统计学意义(P<0.05)。结论早期康复运动干预能够提升脑梗死偏瘫患者治疗有效性,改善其肌力等级、血清指标,提高生命质量、运动功能、神经功能、内皮功能,优化其平衡效能、脑血流动力学。Objective To explore the effect of early rehabilitation exercise intervention on improving muscle strength,movement and quality of life in patients with cerebral infarction hemiplegia.Methods A total of 90 patients with cerebral infarction hemiplegia admitted to Jiujiang First People's Hospital from September 2022 to September 2024 were randomly divided into control group(45 cases)and observation group(45 cases).The control group received routine intervention,and the observation group received early rehabilitation exercise intervention on the basis of the control group.The clinical efficacy,muscle strength grade,serum indexes,quality of life,balance efficacy,cerebral hemodynamics,endothelial function and comprehensive function were compared between the two groups.Results The total effective rate of the observation group(95.56%)was higher than that of the control group(77.78%),and the rate of muscle strength excellent and good(68.89%)was higher than that of the control group(28.89%),the difference was statistically significant(P<0.05).After intervention,serum albumin(Alb),hemoglobin(HGB),lymphocyte(LYM)and fibrinogen(FIB)in observation group were lower than those in control group(P<0.05).After intervention,the scores of GQOL-74(GQOL-74)in the observation group were higher than those in the control group(P<0.05).After intervention,the scores of the modified Fall Efficacy Scale(MFES)and Berg Balance Scale(BBS)in the observation group were higher than those in the control group,and the duration of the standing up and walking timing test(TUGT)was shorter than that in the control group,the difference was statistically significant(P<0.05).After intervention,the resistance index(RI)and pulse index(PI)of the observation group were lower than those of the control group,and the average blood flow velocity(Vm)was higher than that of the control group,with statistical significance(P<0.05).After intervention,peripheral blood endothelial progenitor cells(EPCs)and endothelial nitric oxide synthase(eNOS)in observation group were

关 键 词:早期康复运动 脑梗死偏瘫 肌力 运动 生命质量 

分 类 号:R743.3[医药卫生—神经病学与精神病学] R473.74[医药卫生—临床医学]

 

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