SonoLiver造影定量分析及动态血管模型诊断前列腺病变的价值  

SonoLiver contrast quantitative analysis and dynamic vascular model:an effective auxiliary means for the diagnosis of prostate lesions

作　　者：祖拜热·依斯坎代尔 贾志莺[1] 詹天龙 阿司也木·阿布地里木 张同莉 ZUBAIRE·Yisikandaier;JIA Zhiying;ZHAN Tianlong;ASIYEMU·Abudilimu;ZHANG Tongli(Department of Ultrasound,Cancer Hospital,Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学附属肿瘤医院超声科,新疆乌鲁木齐830000

出　　处：《分子影像学杂志》2025年第4期466-473,共8页Journal of Molecular Imaging

基　　金：教育部产学合作协同育人项目(231106617205328)。

摘　　要：目的探讨SonoLiver造影定量分析及动态血管模型(DVP)诊断前列腺病变的应用价值。方法选取于我院就诊并行前列腺穿刺的患者103例,根据病理结果将其分为前列腺癌组(n=56例)、前列腺增生组(n=22)、前列腺炎组(n=25),比较各组间造影模式(造影增强强度、增强模式、增强是否均匀以及消退时间)、造影参数[最大回声强度比(Imax)、达峰时间(TTP)、上升时间(RT)、上升斜率50%点(Rs50)、上升斜率10%~90%点(Rs1090)、下降时间(FT)、下降斜率50%点(Fs50)、降半时间(FHT)、平均渡越时间(mTT)、灌注期曲线下面积(WinAUC)、灌注率(WinR)、灌出率(WoutR)]和DVP曲线波形。结果前列腺增生组与前列腺恶性组造影模式比较,造影增强强度、增强模式及消退时间的差异有统计学意义(P<0.05),造影增强是否均匀的差异无统计学意义(P>0.05)。前列腺癌组与前列腺炎组造影参数比较,造影增强强度差异有统计学意义(P<0.05),增强模式、增强是否均匀以及消退时间差异均无统计学意义(P>0.05)。前列腺癌组与前列腺增生组造影参数比较,Imax、TTP、RT、Rs50、Rs1090、FT、Fs50、FHT、mTT、WinAUC、WinR、WoutR的差异均有统计学意义(P<0.05);前列腺癌组与前列腺炎组造影参数比较,Imax、TTP、RT、Rs50、Rs1090、Fs50、AUC、WinAUC、WinR、WoutR差异均有统计学意义(P<0.05);前列腺炎组与前列腺增生组造影参数比较,TTP差异有统计学意义(P<0.05)。前列腺癌组中DVP曲线波形以正向波形33.93%(19/56)和正负双向波形57.14%(32/56)为主,前列腺增生组以负正双向波形50.00%(11/22)为主,前列腺炎组以负向波形32%(8/25)、负正双向波形40%(10/25)为主,前列腺癌组DVP曲线波形与其他两组间比较差异有统计学意义(P<0.05)。结论SonoLiver造影定量分析及动态血管模型在前列腺病变诊断中有一定参考价值。Objective To explore the application value of SonoLiver contrast-enhanced quantitative analysis and dynamic vascular model(DVP)in the diagnosis of prostate lesions.Methods A total of 103 patients who visited our hospital and underwent prostate biopsy were selected.According to the pathological results,they were divided into prostate cancer group(n=56),benign prostatic hyperplasia group(n=22),and prostatitis group(n=25).The contrast-enhanced patterns(contrast-enhanced intensity,enhancement pattern,whether the enhancement was uniform,and wash-out time),contrast-enhanced parameters[maximum echo intensity ratio(Imax),time to peak(TTP),rise time(RT),50%point of the rising slope(Rs50),10%-90%point of the rising slope(Rs1090),fall time(FT),50%point of the falling slope(Fs50),fall half time(FHT),mean transit time(mTT),area under the curve during the perfusion phase(WinAUC),perfusion rate(WinR),wash-out rate(WoutR)]and DVP curve waveforms were compared among the groups.Results When comparing the contrast-enhanced patterns between the benign prostatic hyperplasia group and the prostate malignancy group,the differences in contrast-enhanced intensity,enhancement pattern,and wash-out time were statistically significant(P<0.05),while the difference in whether the enhancement was uniform was not statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the prostatitis group,the difference in contrast-enhanced intensity was statistically significant(P<0.05),while the differences in enhancement pattern,whether the enhancement was uniform,and wash-out time were not statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the benign prostatic hyperplasia group,the differences in Imax,TTP,RT,Rs50,Rs1090,FT,Fs50,FHT,mTT,WinAUC,WinR,and WoutR were all statistically significant(P>0.05).When comparing the contrast-enhanced parameters between the prostate cancer group and the prostatitis group,the differences in Im

关 键 词：前列腺肿瘤 超声造影 动态血管模型 定量分析 

分 类 号：R737.25[医药卫生—肿瘤]