机构地区:[1]河南省肿瘤医院神经内科,河南郑州450000
出 处:《中国现代医药杂志》2025年第4期30-34,共5页Modern Medicine Journal of China
摘 要:目的 探讨神经导航下显微外科手术治疗侧脑室脑膜瘤的临床效果及对患者生活质量的影响。方法 对我院2020年1月~2023年12月实施手术治疗的80例侧脑室脑膜瘤患者进行回顾性分析,其中40例采用手术中神经导航+管状脑牵开器+显微外科手术治疗(导航组),另外40例采用管状脑牵开器+显微外科手术治疗(对照组)。对比两组患者治疗前后临床表现、手术情况、生存质量、神经功能评分及并发症。结果 导航组36例达到全切标准、4例次全切,对照组34例达到全切标准、6例次全切,两组肿瘤切除情况差异无统计学意义(χ^(2)=0.457,P=0.499);导航组的皮层切开长度、骨瓣面积均小于对照组,差异具有统计学意义(P<0.05);导航组的平均手术时长短于对照组,差异具有统计学意义(P<0.05);导航组和对照组在手术前后的头痛、头晕、视力障碍、癫痫、肌力下降发生率比较,差异均无统计学意义(P>0.05);术前,导航组和对照组患者的NDS、NIHSS评分比较,差异无统计学意义(P>0.05);术后3个月,导航组的NDS、NIHSS评分均低于对照组,差异有统计学意义(P<0.05);术前,导航组和对照组患者在日常生活能力、心理领域、独立性领域、生理领域及生存质量评分比较,差异均无统计学意义(P>0.05);术后3个月,导航组患者的日常生活能力、独立性领域、生存质量评分均明显高于对照组(P<0.05);导航组术后发生视野缺损9例、脑积水4例、颅内感染2例,对照组术后发生视野缺损12例、脑积水6例、颅内感染4例,导航组并发症发生率为37.50%与对照组的55.00%比较,差异无统计学意义(χ^(2)=2.464,P=0.116)。结论 神经导航下显微外科手术治疗侧脑室脑膜瘤有利于缩短手术时间、减小手术需要的骨瓣面积,有助于术后神经功能及生活质量的提高。Objective To investigate the clinical effect and quality of life of neuronavigational microsurgery in the treatment of lateral ventricle meningioma.Methods A retrospective analysis was performed on 80 patients with lateral ventricle meningioma who underwent surgical treatment in our hospital from Jan 2020 to Dec 2023.Among them,40 patients were treated with intraoperative neuronavigation+tubular brain retractor+microsurgery(navigation group),and other 40 patients were treated with tubular brain retractor+microsurgery(control group).The clinical manifestations,operation status,quality of life,neurological function score and surgical complications were compared between the two groups before and after treatment.Results In the navigation group,36 cases met the criteria for total resection and 4 cases met the criteria for subtotal resection,while in the control group,34 cases met the criteria for total resection and 6 cases met the criteria for subtotal resection.There was no significant difference in tumor resection between the two groups(χ^(2)=0.457,P=0.499).The incision length of the cortex and the area of the bone flap in the navigation group were lower than those in the control group,with statistical significance(P<0.05).The average length of operation in the navigation group was significantly different from that in the control group(P<0.05).Comparing the incidence of headache,dizziness,visual impairment,epilepsy and muscle strength before and after surgery,the differences were not statistically significant(P>0.05).Before surgery,there were no statistically significant differences in NDS and NIHSS scores between the navigation group and the control group(P>0.05);Three months after surgery,the NDS and NIHSS scores of the navigation group were lower than those in the control group,and the differences were statistically significant(P<0.05);Before surgery,there were no statistically significant differences between the navigation group and the control group in terms of daily living ability,psychological domain score,
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