中国与日本胃癌治疗成绩比较——附2438例报告  

Comparison for treatment experience of gastric cancer between china medical university and university of Tokyo-A report of 2438 Cases

作　　者：戚晓东[1] 陈波[2] 王江[2] 魏政立[2] 金锋[2] 王舒宝[2] 陈峻青[2] 真船健一[3] 上西纪夫[3] 

机构地区：[1]北京同仁医院肿瘤外科,100730 [2]中国医科大学肿瘤外科,110001 [3]日本东京大学消化管外科

出　　处：《辽宁医学杂志》2002年第5期238-240,共3页Medical Journal of Liaoning

摘　　要：目的　通过比较中国医科大学 (中国医大 )和日本东京大学 (东大 )胃癌诊疗成绩 ,探讨提高胃癌治疗方法。方法　比较两大学之间胃癌的临床病理特征、手术方式的分布特点及其对术后长期生存影响。结果　东大的治愈性切除率为 85 9% (914 10 6 4 ) ,高于中国医大的 6 7 5 % (75 6 112 0 )。中国医大高度进展期癌 (se ,si)占治愈性切除的 5 2 1% (394 75 6 ) ,远高于东大的 16 6 % (15 2 914 ) ;中国医大治愈性切除病例的早期癌占 17 3% (131 75 6 ) ,低于东大的 5 7 2 % (5 2 3 914 )。东大的胃癌治愈性切除术后总生存率明显高于中国医大 (77 2 % ,5 7 1% ,P <0 0 0 0 1)。两大学资料都显示 ,癌浸润深度越深 ,预后越差 ;D2 ,D3根治术 5年生存率均高于D1 根治术 ;手术方式不同 ,其生存率顺序为远切 >全切 >近切 >联合切 ;浸润型胃癌预后差。Objective Comparison of treatment experience of gastric cancer between China Medical University (CMU) and University of Tokyo (TU) had been investigated in the past years, so as to evaluate its treatment methods for gastric cancer Methods Comparison of clinical and pathological factors, operation styles and survival rate of patients underwent curative resection of gastric cancer had been investigated between two university Results Curative resection rate in TU was 85 9%(914/1064), significantly higher than that in CMU, as 67 5%(756/1120), while, in the group of advanced gastric cancer (the depth of cancer invasion: Se, Si) higher curative resection rate could be found in CMU, as 52 1%(394/756), comparing to that in TU, as 16 6%(152/914) In the cases with curative resection, significantly lower rate of early gastric cancer could be found in CMU, as 17 3%(131/756),comparing to that in TU, as 57 2%(523/914)? Survival rate in the group with curative resection in TU was significantly higher than that in CMU, as 77 2% and 57 1%, respectively (P<0 0001)?Our results showed that, after comparative investigation, deeper invasion, worse survival rate could be investigated in total of cases of both universities Both of the five years survival rates underwent D 2 or D 3 curative resection were higher than that underwent D 1, respectively The sequence of five years survival rates among different operative style as follow: distal gastrectomy>total gastrectomy>proximal gastrectomy>associated organ resection, and the patients with infiltrative histopathological proliferation showed worse outcome after curative resection Conclusions All of our results in this paper suggested that it would be the key step to elevate discovery rate of early gastric cancer and formulate the treatment method of curative resection for up regulating treatment achievement

关 键 词：中国 日本 胃癌 手术方式 治疗成绩 病理特征 对比分析 

分 类 号：R735.2[医药卫生—肿瘤]