颞下颌关节盘前移后双板区改建的实验研究  

The Experimental Study on Remodeling in the Bilaminar Zone of Temporomandibular Joint Following Disc Displacement

作　　者：谷志远[1] 冯剑颖[1] 詹静[1] 吴慧玲[2] 柴田.考典[3] 

机构地区：[1]浙江大学医学院附属口腔医院,310006 [2]浙江大学医学院附属第一医院 [3]日本山形大学

出　　处：《华西口腔医学杂志》2002年第6期408-410,共3页West China Journal of Stomatology

摘　　要：目的:探讨关节盘前移后双板区的适应性改建。方法:日本大白兔30只,先制作成关节盘前移位动物模型,定期处死,取关节标本作HE染色、阿尔辛蓝、间苯二酚-品红染色、细胞凋亡检查和蛋白多糖含量测量。结果:在关节盘移位的初期,双板区即发生细胞凋亡,胶原纤维和弹力纤维排列紊乱、断裂;蛋白多糖先是急剧下降,然后缓慢上升。4周后,双板区内可出现软骨样细胞或典型的软骨组织。结论:双板区在关节盘移位后会进行重构,使之成为类似纤维软骨样组织。Objective:The purpose of this study was to study the adaptive alterations in the bilaminar zone (BZ) of temporomandibular joint following disc displacement. Methods: Thirty Japanese white rabbits were used in this study. The right joints of 24 rabbits were subjected to surgical disc displacement (DD) . The sections were studied using hematoxylin and eosin, Alcin bluin and Res-orcin-fuchsin staining, and in situ detection of apoptosis.Results: Apoptotic chondrocytes in bilaminar zone were most obviously at 1 or 2 weeks after operation. Following alterations could be also found in bilaminar zones using microscopy: derangement, fragment, hylination of collagen fibers and diminution in the number of cell. Elastic fibers reduced in number and ran irregularly. Conclusion: The bilaminar zone will be remodeled following disc displacement and become a disc-like tissue. So, the bilaminar zone may function as a disc after disc displacement.

关 键 词：颞下颌关节 关节盘移位 双板区 适应性改建 颞下颌关节紊乱病 TMD 

分 类 号：R782.6[医药卫生—口腔医学]