食管癌肉瘤临床病理学观察  

Observation of the development of esophageal carsinosarcoma

作　　者：张洪福[1] 刘黎明 尹秋伟[1] 唐卫华[3] 

机构地区：[1]山东大学齐鲁医院胸外科 [2]青岛海慈医院胸外科 [3]山东大学齐鲁医院病理科

出　　处：《山东大学学报（医学版）》2002年第6期563-564,共2页Journal of Shandong University:Health Sciences

摘　　要：目的:通过6例食管癌肉瘤临床及病理资料结合文献资料,探讨食管癌肉瘤发生、发展特征。方法:将早期食管癌与肉瘤单独或共存的病理切片在镜下观察摄片,了解癌与肉瘤的解剖关系。结果:发现食管癌肉瘤有三种存在形式:①食管早期浸润癌与肉瘤单独存在;②早期浸润癌与肉瘤共存,二者间界限分明;③癌组织与肉瘤混杂生长。结论:推断某种致癌化学物质或病毒攻击免疫功能低下的食管肉瘤表面、基底、对侧食管粘膜,致其基因突变,形成原位癌、早期浸润癌,并逐渐侵入肉瘤或更深。食管肉瘤与食管癌存在因果关系。Objective:After studied the clinical and pathological status of 6esophageal carcinosarcoma cases,combining with literature data,we summed up the occurrence and development characteristics of esophageal carcinosarcoma.Methods:We made pathological sections of early esophageal carcinoma,sarcoma or mixed,and observed by the help of high power microscope and took pictures of them.Then we understood the relationship between carcinoma and sarcoma.Results:There were3existing patterns of esophageal carcinosarcoma.First was the existence alone of esophageal early invasion carcinoma and sarcoma.Second was the coexistence of early invasion carcinoma and sarcoma.Third was the growing mixed of carcinoma and sarcoma.Conclusion:We deduce that there are some oncogenic chemical substances or virus attacking the surface,basement of sarcoma with hypoimmunity or its contralateral esophageal mucosa,and evokes gene mutation,then forms carcinoma in situ or early invasion carcinoma.The carcinoma in situ or early invasion carcinoma invades the sarcoma gradually.The sarcoma and esophageal carcinoma is cause and effect.

关 键 词：食管癌肉瘤 临床 病理学 

分 类 号：R735.1[医药卫生—肿瘤]