中枢型神经纤维瘤病的临床表现与MR影像特征(附4例报告及文献复习)  

Clinical manifestations and MRI fea tures of central neurofibromatosis:a report of 4cases and the review of l iterature

作　　者：王琦[1] 张永利[1] 肖来柱[1] 郭雅茹[1] 欧阳雪晖[1] 王银柱[1] 

机构地区：[1]内蒙古自治区医院介入放射科MR室,呼和浩特市010017

出　　处：《实用医学影像杂志》2002年第4期244-247,共4页Journal of Practical Medical Imaging

摘　　要：目的研究中枢型神经纤维瘤病(神经纤维瘤病2型,NF2)的临床表现与MR影像特征。方法4例可疑NF2患者于临床症状出现或加重后3周至2年内行头颅Gd-DTPA增强前后MRI检查,NF2的MRI诊断得到手术与病理证实。同时,记录了每例患者的临床表现。结果MRI平扫显示,NF2病灶的特征性表现为T1WI上呈低、等信号,而在T2WI上呈高信号。Gd-DTPA增强后,病灶呈明显强化。MRI还证实了4例NF2患者均合并脑膜瘤,这些患者最常见的症状是进行性耳聋、耳鸣、眩晕,步态不稳。结论NF2具有恒常的能通过对比增强MR像证实的强化特征。因此,头颅Gd-DTPA增强前后MRI检查应成为诊断NF2的主要手段。Objective To investigate the clinical manifestations and MRI features of central neurofibromatosis(neurofibromatosis type2,NF2).Methods Four patients with clinically suspected NF 2underwent MRI examinations of the brain with and without Gd -DTPA enhancement within three weeks to tw o years after onset or exacerbation o f clinical symptoms.MRI diagnoses o f NF 2in all patients were confirmed by the operation and the pathology.Simultaneously,clinial m anifestations were reorded for each patient.Results MR Plain seans showed that,all the lesions in 4case s were hypointese,isointense on T 1 WI and hyperintense on T 2 WI.On Gd -DTPA enhanced images,the lesions were obviously enhanced.MRI also demonstrated that.all patien ts complicated with meningioma.The commonest presenting symp-toms of these patients were progressive deafness,tinnitus,dizziness a nd unsteadiness.Condusion NF2have consistent enhancernent fe atures that can be demonstrated with contra st enhanced MR imaging and therefore MRI examination of brain with and without Gd -DTPA en-hancement should be the preferred me ans of diagnosing NF2.

关 键 词：诊断 中枢型神经纤维瘤病 临床表现 MR 影像特征] 

分 类 号：R739.4[医药卫生—肿瘤]