介入加中药治疗中晚期肝癌的临床观察  

Treatment of advanced primary liver cancer by Traditional Chinese medicines and infusion chemotherapy and chemoembolization

作　　者：李明淑[1] 金花[1] 张蓉[1] 金庆文[1] 邓旭光[1] 

机构地区：[1]深圳市第二人民医院,广东深圳518035

出　　处：《深圳中西医结合杂志》2002年第6期344-345,353,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的观察介入加中药治疗中晚期肝癌的临床疗效及价值。方法 单纯介入组16例,采用TAE方法,化疗药物选用ADM(或Epi-ADM、THP-ADM)、MMC、DDP、5-FU。栓塞使用lipidol混悬液。介入加中药组14例,介入方法及化疗药物同单纯介入组。中医中药治疗以辨证论治为主。结果 近期疗效以治疗前和治疗后1～3个月肝脏CT或MRI检查结果对比作为评价标准。单纯介入组与介入加中药组肿瘤缩小情况比较,无显著差异。3个月、6个月、12个月、18个月及24个月生存情况表明介入加中药组明显优于单纯介入治疗组,中位生存时间分别为9个月、5个月。介入加中药治疗改善中晚期肝癌患者的临床症状较迅速,并持续无症状时间较长,生存质量明显提高。结论介入加中药是治疗中晚期肝癌的一种合理、有临床意义的结合方法。Objective To observe the efficacy of the traditional Chinese medicines and hepatic artery infusion chemotherapy and chemoembolization in the treatment of advanced primary liver cancer. Methods Of the 30 patients, only infusion chemotherapy and chmoembolization was performed in 16 patients,and traditional Chinese medicines and infusion chemotherapy and chemoembolization in 14 patients. Chemotherapy was carried out with a combination of ADM(or Epi - ADM) ,MMC,DDP,5-FU. Embolization was carried with lipidol. Traditional Chinese medicines was accomplished with diagnosis and treatment based on an overall analysis of the illness and the patients condition. Results Response rates were assessed by CT or MRI scanning. The response rate of the only infusion chemotherapy and chemoembolization group was similar to the other group. The 3,6,12,18 and 24 month survival rate of the traditional Chinese medicines group was higher than the rate of the other group. The median of the survival period was 9 months and 5 months, respectively . And the clinical symptoms were relieved more obvious and longer in the cases of the traditional Chinese medicines group. Conclusion Treatment by traditional Chinese medicines and infusion chemotherapy and chemoembolization is of benefit to the patients with advanced primary liver cancer.

关 键 词：原发性肝癌 化学栓塞 中医中药治疗 

分 类 号：R735.705[医药卫生—肿瘤]