羧甲基纤维素支载三亚乙基四胺催化Knoevenagel反应  

Carboxymethyl Cellulose Supported Triethylenetetramine as a Catalyst for Knoevenagel Condensation

作　　者：李毅群[1] 周美云[1] 徐欣明[1] 欧亦群[2] 

机构地区：[1]暨南大学化学系 [2]暨南大学食品科学与工程系,广州510632

出　　处：《应用化学》2003年第1期89-91,共3页Chinese Journal of Applied Chemistry

基　　金：中国科学院广州化学研究所纤维素化学重点实验室访问学者基金资助 (LCLC 2 0 0 2 137)

摘　　要：The Knoevenagel reaction of aromatic aldehydes with malononitrile and ethyl cyanoacetate proceeds smoothly in the presence of carboxymethyl cellulose supported triethylenetetramine as catalyst in the 95% ethanol to afford the desired E-isomers of the corresponding alkenes in yield of 74%～96% and good purity. The results confirm that the catalyst can offer definite advantages of good activity , easy separation, mild reaction condition and high yields. Moreover, it can be reused for not less than 5 runs.The Knoevenagel reaction of aromatic aldehydes with malononitrile and ethyl cyanoacetate proceeds smoothly in the presence of carboxymethyl cellulose supported triethylenetetramine as catalyst in the 95% ethanol to afford the desired E-isomers of the corresponding alkenes in yield of 74%～96% and good purity. The results confirm that the catalyst can offer definite advantages of good activity , easy separation, mild reaction condition and high yields. Moreover, it can be reused for not less than 5 runs.

关 键 词：羧甲基纤维素支载三亚乙基四胺 催化剂 KNOEVENAGEL反应 烯烃 合成 

分 类 号：O623.12[理学—有机化学] O621.36[理学—化学]