进展期胃癌根治性术后腹腔内化疗的疗效评价  

Assessment on the efficacy of intraperitoneal chemotherapy on progressive gastric cancer after radical treatment

作　　者：王彩莲[1] 陈宝安[1] 姜藻[1] 张琳[1] 戴文俊[1] 胡洁[1] 张航[1] 

机构地区：[1]东南大学附属中大医院肿瘤科,江苏南京210009

出　　处：《中国癌症杂志》2002年第6期546-547,共2页China Oncology

摘　　要：目的:观察进展期胃癌根治性手术后腹腔内化疗的疗效。方法:选择Ⅱ-Ⅲ期的根治性胃癌手术后病人64例,随机分成两组,分别为全身化疗+腹腔内化疗组和全身化疗组,统计两组的三年复发率、三年生存率。结果:治疗组三年复发率为18.75％,对照组为43.33％(P<0.05),治疗组三年生存率为84.38％,对照组为60％(P<0.05)。结论:全身静脉化疗结合腹腔内化疗治疗进展期胃癌手术后病人的疗效优于单纯全身静脉化疗。Purpose: To observe the efficacy of intraperitoneal chemotherapy on advanced gastric cancer after radical treatment. Methods: 64 cases of patients with stage Ⅱ - Ⅲ treated by radical surgery were selected and randomly divided into systematic plus intraperitoneal chemotherapy group and systemic chemotherapy group. 3-year survival rate and 3-year recurrence rate were recorded. Results: The recurrence rate for the intraperitoneal chemotherapy group was 18.75% while the control was 43. 33% (P <0. 05); and the survival rate for the intraperitoneal chemotherapy group was 84.38% while the control was 60%, P < 0. 05. Conclusions: Using systematic plus intraperitoneal chemotherapy in treating advanced gastric cancer after radical treatment is superior to systematic chemotherapy only.

关 键 词：进展期胃癌 腹腔内化疗 复发率 生存率 治疗 

分 类 号：R735.205[医药卫生—肿瘤]