肿瘤多药耐药性及其逆转剂研究进展  

Advances of study on tumor multi-drug-resistance and reversal agents

作　　者：张肃[1] 梁钢[1] 

机构地区：[1]广西医科大学药理学教研室,南宁530021

出　　处：《中国药理学通报》2002年第6期615-618,共4页Chinese Pharmacological Bulletin

基　　金：广西壮族自治区科技厅自然科学基金资助 No桂科自 0 0 0 430 2

摘　　要：肿瘤细胞的多药耐药性 (MDR)成为目前肿瘤化疗的难点。MDR的产生机制有多种 ;同时有多种具有逆转作用的药物被发现。The multi drug resistance(MDR) of tumor cells has become a difficult problem in the chemotherapy of tumor, meanwhile, the mechanism of MDR are various:relevant drugs with reversal effects have been discovered. This review will provide the most impossible mechanisms of MDR and some prospecting reversal drugs.

关 键 词：研究进展 肿瘤 多药耐药 耐药机制 逆转剂 化疗 

分 类 号：R730.53[医药卫生—肿瘤]