利培酮与舒必利治疗以阴性症状为主的精神分裂症对照研究  

A comparative study on Risperidone and sulpiride in treating schizophrenia whose predominant clinical features were negative symptoms

作　　者：刘冬青[1] 邱春英[1] 刘艳荣 

机构地区：[1]山东省滨州市人民医院精神卫生中心,山东滨州256613 [2]山东省滨州市旧镇医院,山东滨州256613

出　　处：《中国民康医学》2003年第1期15-17,共3页Medical Journal of Chinese People’s Health

摘　　要：目的 :探索利培酮对以阴性症状为主的精神分裂症的疗效与副反应。方法 :对 80例以阴性症状为主的精神分裂症住院患者 ,用利培酮与舒必利随机对照 ,采用阳性与阴性症状量表 (PANSS)、阴性症状评定量表 (SANS)和临床疗效总评量表 (CGI -GI)评定疗效 ,副反应量表 (TESS)评定副作用。结果 :利培酮与舒必利疗效相当 ,而副反应严重程度低于舒必利。结论 :利培酮是治疗以阴性症状为主的精神分裂症较理想的药物。Objective:To probe into clinical therapy and side effect with risperidone in the treatment of schizophrenia whose predominant clinical features were negative syptoms Method:80 cases of schizophrenia whose predominant clinical features were negative syptoms were randomly assigned to treat with either risperidone or sulpiride Efficacy result were assessed by PANSS,SANS,CGI-GI,and side effects by TESS Results:The effective rates of this two groups were similar The serious degree of side effect was lower in risperidone group than that of sulpiride Conclusion:Risperidone is preferred as an ideal agent in the treatment of schizophrenia whose predominant clinical features were negative symptoms

关 键 词：精神分裂症 阴性症状 利培酮 舒必利 治疗 

分 类 号：R749.305[医药卫生—神经病学与精神病学]