晚期食管癌姑息性切除489例分析  

Palliative Operation for Advanced Esophageal Carcinoma ——Analysis of 489 Cases

作　　者：刘平[1] 李启驹[1] 

机构地区：[1]河南省新乡市中心医院肿瘤外科,新乡453000

出　　处：《河南职工医学院学报》2002年第4期296-297,301,共3页Journal of Henan Medical College For Staff and Workers

摘　　要：目的　研究姑息性手术对晚期食管癌病人预后的影响。方法　从 1 985年到 1 994年 ,489例晚期食管癌病人接受了姑息性手术 ,病人被根据有或没有远处转移而分成两组 ,对比分析病人的临床病理特征和预后。结果　在没有远处转移的病例中 ,肿瘤主要侵润相邻的组织和切缘残留 ,无淋巴结的转移。在有远处转移的病例中 ,纵隔淋巴结和颈部淋巴结均有转移。没有远处转移的病人其生存率要好于有远处转移的病人 (P <0 0 1 )。结论　没有远处转移的病人在手术中要尽可能地切除原发肿瘤和相邻的淋巴结 ,加以术后放疗 ,能延长病人的生存时间 ,对于有远处转移的晚期食管病人 。Objective To study and evaluate the clinical value of palliative operation for advanced esoph ageal carcinoma.Methods Between 1985 and 1994,489 patien ts with advanced esophageal carcinoma who were treated with esophagogastrostomy defined as a pall iative operation.The patients were divided into two groups:locally advanced cancer and cancer with a distant metastasis.The clinicopathological features and prognosis of these patient s were examined. Results In locally advanced cancer cases,tumor cells rem ained in the neighboring organs and resected margins,no lymph nodes metastasis,i n those with distant meatastasis,mediastinal lymph node metastasis and cervical lymph node metastasis.The survival rate for patients with locally advanced esoph ageal carcinoma was better than that of patients with distant metastasis( P < 0 01).Conclusion Survival time in patients with loca lly advanced cancer can be lengthened by resecting all of the primary tumor and as much of the neighboring lymph nodes as posible even if the surgical managemen t is palliative resection.Aggressive postoperative radiotherapy with distant met astasis from an esophageal carcinoma is to be recommended. [

关 键 词：晚期 食管癌 姑息性切除 转移 预后 

分 类 号：R735.1[医药卫生—肿瘤]