钩藤对家兔癫癇模型电活动的调制  

Modulation of Uncaria on Brain Electrical Activities of Rabbit Epileptic Model

作　　者：郑开俊[1] 徐淑梅[1] 何津岩[1] 仇晓菁[1] 林来祥[1] 

机构地区：[1]天津医科大学生理教研室,300070

出　　处：《天津医药》2003年第1期35-36,共2页Tianjin Medical Journal

摘　　要：目的:研究钩藤对癫癇发作的影响。方法:采用脑电图描记术,观察钩藤对毛果芸香碱致癇家兔大脑皮层放电的影响。结果:腹腔注射钩藤后可使癫(?)发作次数及发作持续时间显著减少,发作间隔时间显著延长(P<0.05)。结论:钩藤注射液能明显抑制癫痫模型电活动,提示钩藤具有抗癇作用。Objective: To study the modulation of uncaria on brain electrical activities of rabbit epileptic model. Methods: The rabbits injected with pilocarpine served as the epileptic models. The effect of uncaria on electroencephalogram of the epileptic models was observed. Results: After intra-abdominal cavity injection of uncaria, the seizure times and duration of each major seizure of epilepsy were significantly decreased, and the interval of seizure was significantly prolonged(P<0.05) .Conclusion: Because the uncaria can inhibit the brain electrical activities of epileptic model,it has the distinct effect of anti-epilepsy.

关 键 词：钩藤 癫痫 脑电描记术 

分 类 号：R277.721[医药卫生—中医学]