Adaptive alterations of elastic fibers in the bilaminar zone of rabbit temporomandibular joint following disc displacement  

兔关节盘移位后双板区弹力纤维的适应性变化(英文)

作　　者：谷志远[1] 吴慧玲[2] 冯剑颖[1] 柴田考典[3] 胡济安[1] 张银凯[1] 谢志坚[1] 

机构地区：[1]浙江大学医学院附属口腔医院口腔颌面外科,杭州310006 [2]浙江大学医学院附属第一医院外科,杭州310006 [3]日本山形大学医学部口腔颌面外科

出　　处：《Chinese Medical Journal》2002年第12期1772-1776,144,共5页中华医学杂志（英文版）

摘　　要：OBJECTIVE: To study the adaptive alterations of elastic fibers in the bilaminar zone (BZ) of rabbit temporomandibular joint (TMJ) following disc displacement. METHODS: Twenty-eight Japanese white rabbits were used in this study. The right temporomandibular joints of 20 of 28 rabbits were subjected to the surgical procedure of anterior disc displacement (ADD). Four rabbits in the surgical group were sacrificed at 2, 4, 6, 8 and 12 weeks after operation. Their temporomandibular joints were studied histochemically. RESULTS: Elastic fibers were reduced in number and ran irregularly in the superior lamina of BZ from ADD rabbits. The jungly elastic fibers (EFs) could still be seen at 2 weeks after operation. At 4 weeks, the number of EFs decreased significantly; EFs lost their jungly arrangement and were shaped like rough dots, of which the arrangement and the lengths were different. Six weeks after operation, many EFs were replaced by distorted, uneven, non-oriented fine EFs, distributed unevenly and some thick or fine EFs that ran irregularly. The number of EFs decreased further and their arrangement was more deranged at 8 weeks. At 10 and 12 weeks, EFs in the superior lamina of BZ were similar to those at 8 weeks. CONCLUSION: Our results show that EFs lost their function as well as their distribution and arrangement after disc displacement.目的　探讨颞下颌关节盘中弹力纤维在关节盘前移位后的动态变化。方法　日本大白兔 2 8只 ,8只用于实验对照 ,2 0只用于建立右关节盘前移位动物模型。分别于术后 2周、4周、6周、8周和 12周各处死 4只实验动物 ,作组织化学检查。结果　实验组中双板区的弹力纤维在盘前移位后出现纤维数量下降及排列紊乱。 2周时可见丛状弹力纤维 ;4周时弹力纤维数量明显下降 ,丛状排列消失 ,纤维断裂 ;6周时弹力纤维扭曲或断裂成粗黑点 ;8周时纤维数量进一步减少 ,排列明显紊乱 ;10周和 12周与 8周相似。结论　关节盘前移位后双板区弹力纤维的功能、分布和排列均发生了变化。

关 键 词：Adaptation  Physiological ANIMALS Behavior  Animal Dislocations Elastic Tissue Extracellular Matrix RABBITS Temporomandibular Joint Disk Temporomandibular Joint Disorders 

分 类 号：R782.6[医药卫生—口腔医学]