Comparison of pre- and post-operational multifocal electroretinograms of retinal detachment  

视网膜脱离术前和术后的多焦视网膜电图比较

作　　者：吴德正[1] 高汝龙[1] 张国明[1] 吴乐正[1] 

机构地区：[1]中山大学,中山眼科中心,卫生部眼科学实验室,广州,510060

出　　处：《Chinese Medical Journal》2002年第10期1560-1563,共4页中华医学杂志（英文版）

摘　　要：OBJECTIVES: To explore the changes of multifocal electroretinograms (mfERG) before and after retinal detachment surgery and to evaluate its clinical significance. METHODS: Twenty-three patients (23 eyes) with rhegmatogenous retinal detachment underwent mfERG before and after surgery. The latencies and average response densities of N(1)-wave and P(1)-wave of mfERGs in detached areas, attached areas, fovea and the entire tested area were compared before and after surgery. RESULTS: Preoperatively, the average response densities of N(1)-wave and P(1)-wave in the detached area were significantly smaller than those in attached areas (t = 3.68, t = 4.26, P 0.05). CONCLUSIONS: The mfERG is a useful tool to evaluate the recovery of posterior retinal function after retinal detachment surgery. The response density is a more sensitive index than latency to evaluate retinal function of retinal detachment.目的探讨视网膜脱离术前和术后多焦视网膜电图(multifocal electroretinogram,mfERG)的改变及评价其临床应用价值.方法 23例(23只眼)患裂孔源性视网膜脱离患者手术前后分别进行了mfERG检查.于脱离区,非脱离区,中心凹及整个测试区,对手术前和手术后mfERG的N1波和P1波的潜伏期和平均反应密度进行比较.结果手术前脱离区的N1波和P1波的平均反应密度明显小于非脱离,差异有显著性意义(t =3.68,t4.26,P<0.01),脱离区的N1波和P1波潜伏期时明显比非脱离区延长 ,差异有显著性意义(t=3.07,t=3.89,P<0.01).手术后于脱离区,中心凹和整个测试区的N1波和P1波平均反应密度较术前明显增大(P<0.05),但N1波和P1波的潜伏期则无明显变化(P>0.05).结论 mfERG是评价术后视网膜功能恢复的有用工具,对视网膜功能测试反应密度较潜伏期为更敏感的指标.

关 键 词：ELECTRORETINOGRAPHY ADULT Aged Comparative Study FEMALE Humans MALE Middle Aged Retinal Detachment Visual Acuity 

分 类 号：R779.6[医药卫生—眼科]