Multifocal electroretinograms in the early stages of diabetic retinopathy  

早期糖尿病视网膜病变的多焦视网膜电图及临床意义

作　　者：余敏忠[1] 张欣[1] 钟兴武[1] 于强[1] 江福钿[1] 马娟妹[1] 吴德正[1] 

机构地区：[1]卫生部眼科学实验室,中山大学中山眼科中心,广州,510060

出　　处：《Chinese Medical Journal》2002年第4期563-566,共4页中华医学杂志（英文版）

摘　　要：OBJECTIVE: To investigate the characteristics of multifocal electroretinograms (mf-ERG) of different phases in diabetic retinopathy (DR) and its clinical significance. METHODS: Multifocal electroretinograms in patients with DR (I - II stage) were tested with VERIS IV system. RESULTS: In I - II stage, the absolute values of N1, P1 and N2 response densities, and the N1-P1 and P1-N2 response densities were attenuated is a field of about 45 degrees in diameter. CONCLUSION: As a new objective and quantitative examination for spatial visual function, multifocal electroretinograms may be valuable in the diagnosis of diabetic retinopathy.目的研究早期糖尿病视网膜病变的多焦视网膜电图特征及其临床意义.方法采用VERIS Ⅳ视觉诱发反应图象系统测量和分析糖尿病视网膜病变Ⅰ-Ⅱ期34眼的多焦视网膜电图改变.结果在直径约45度的测试范围内6个离心度的环状区和4个象限,Ⅰ-Ⅱ期糖尿病视网膜病变与正常对照眼比较,N1波、P1波和N2波的反应密度绝对值以及N1-P1和P1-N2反应密度峰-峰值显著降低.结论在糖尿病视网膜病变发展过程中多焦视网膜电图反应密度已经出现异常,多焦视网膜电图作为一种客观定量的视觉空间功能检查新方法,对糖尿病视网膜病变的具有早期诊断的价值.

关 键 词：Aged Diabetic Retinopathy ELECTRORETINOGRAPHY FEMALE Humans MALE Middle Aged RETINA Time Factors 

分 类 号：R587.2[医药卫生—内分泌] R774.[医药卫生—内科学]