螺旋CT经动脉门脉造影扫描时间窗的临床研究——造影剂注射速率对螺旋CTAP动态增强的影响  

Clinical Study of Optimal Time Window for Liver Scanningwith Helical CT During Arterial Portography——The Effect of the Injection Rate of Contrast Medium on HepaticDynamic Enhancement with Helical CT During Arterial Portography

作　　者：金泳海[1] 丁乙[1] 刘一之[1] 倪才方[1] 朱晓黎[1] 孙鸽[1] 邢建明[1] 

机构地区：[1]苏州大学附属第一医院放射科,江苏苏州215006

出　　处：《实用放射学杂志》2002年第12期1064-1067,共4页Journal of Practical Radiology

摘　　要：目的　研究造影剂注射速率对螺旋CTAP动态增强的影响 ,寻找适宜的注射速率。方法　 3 2例肝癌患者分成四组。经肠系膜上动脉注入浓度为 2 2 5mg/ml的泛影萄胺 80ml ,注射速率分别为A :3 .0ml/s ;B :2 .5ml/s ;C :2 .0ml/s ;D :1.5ml/s ,选一固定层面作 2 5次单层动态扫描 ,间隔时间 3s。测定每幅图像上肝实质和肿瘤的CT值 ,分别画出时间—密度曲线。分析肝实质和肿瘤动态增强特征。结果　①四组肝实质增强峰值时间 (s)分别为A :3 4.6± 5 .4;B :3 7.2± 4.2 ;C :3 9.1± 3 .8;D :49.7± 5 .1。A、B、C之间无显著性差异 (Ρ >0 .0 5 ) ,A、B、C与D之间有显著性差异 (Ρ <0 .0 1)。②四组肝实质增强峰值 (HU )分别为A :187.5± 13 .1;B :183 .8± 11.2 ;C :178.4± 7.8;D :165 .3± 8.9。A、B、C之间无显著性差异 (Ρ >0 .0 5 ) ,A、B、C与D之间有显著性差异 (Ρ <0 .0 1)。③四组肿瘤均无明显增强。结论　当造影剂用 2 2 5mg/ml的泛影萄胺 80ml时 ,①采用 2 .0～ 3 .0ml/s注射速率优于 1.5ml/s。②在造影剂 2 .0～ 3 .0ml/s注射速率范围内 ,螺旋CTAP增强特征与速率无关。因此选用 2 .Objective To study the effect of the injection rate of contrast medium on hepatic dynamic enhancement with helical CT during arterial portography,to determine the optimal injection rate of contrast medium.Methods Thirty-two patients were divided into A,B,C and D groups.A volume of 80 ml of megluming diatrizoate(225 mg/ml) was injected with a power injector into the SMA in all patients.The injection rates were,A:3.0 ml/s;B:2.5 ml/s;C:2.0 ml/s;D:1.5 ml/s.25 repeated scans were obtained with an interscan delay of 3 seconds at a single level after contrast material injection.To measure the attenuation of the liver parenchyma and tumors on every scan,and time-attenuation curves were created.Dynamic enhancement characteristics of the live parenchyma and tumors were evaluated.Results ①The time to peak of attenuation of hepatic parenchyma in groups A,B,C and D were (34.6±5.4) s;(37.2±4.2) s;(39.1±3.8) s;(49.7±5.1) s,respectively.Among groups A,B and C,there were not significant difference(Ρ>0.05),but between A,B,C and D,the difference were significant(Ρ<0.01).②The peak of enhancement of hepatic parenchyma in group A,B,C and D were (187.5±13.1) HU;(183.8±11.2) HU;(178.4±7.8) HU;(165.3±8.9) HU,respectively.Among groups A,B and C,there were not significant difference(Ρ>0.05),but between A,B,C and D,the difference were significant(Ρ<0.01).③There were not various in the attenuation of the tumors.Conclusion When a volume of 80 ml of megluming diatrizoate(225 mg/ml) was injected,①the injection rates(2.0～3.0 ml/s) is supperior to the rate(1.5 ml/s).②within the range of the rates (2.0～3.0 ml/s),the enhancement characteristics of the liver is not effected by the injection rate.So the rate(2.0 ml/s)is optimal.

关 键 词：肝癌 动态增强 体层摄影 X线计算机 

分 类 号：R735.7[医药卫生—肿瘤] R814.[医药卫生—临床医学]