生姜对高血脂大鼠脂质过氧化作用的研究  

Effect of Zingiber officinale rosc on lipid peroxidation in hyperlipidemia rats

作　　者：刘宁[1] 霍贵成[1] 张玲[2] 张学艳[2] 

机构地区：[1]东北农业大学食品学院,哈尔滨150030 [2]东北农业大学医院

出　　处：《卫生研究》2003年第1期22-23,共2页Journal of Hygiene Research

摘　　要：生姜是中国人日常食用的根茎类食物 ,也是中药材 ,有许多药理学功能。最近研究表明 ,生姜不仅能降低血脂水平 ,而且能使小鼠动脉粥样硬化区域减少 ,但其作用机理尚不清楚。本文研究生姜对高脂大鼠抗氧化作用 ,观察其血中GSH Px和LPO的变化。雄大鼠分为对照、预防和治疗组 ,在各实验组饲料中分别加入 2 %和 5 %的生姜 ,实验结束测定血液中GSH Px和LPO。结果显示 ,各实验组较对照组GSH Px有不同程度的升高 ,LPO有不同程度的降低。生姜可以对体内自由基有不同程度的抑制和Zingiber Officinale Rosc(ginger) is the food of rhizoma species as well as Chinese traditional medicine and has various pharmacological effects. The last researches showed that ginger not only reduced plasma lipid levels but also the mouse atherosclerotic lesion areas. The ginger antioxidative effect maybe pay an important role in attenuation of development of atherosclerosis. Antioxidative effect of Zingiber Officinale Rosc on hyperlipidemia rats have been studied and the changes of GSH Px and LPO in their blood have been observed in this paper. Male adult Wistar rats were grouped into control, preventiv and curative teams. The experimental teams were respectively fed on the test diet containing 2% ginger and 5% ginger, in order to measure the changes of plasma lipid peroxides (LPO) and glutathione (GSH Px) after the experiment. The results show that ginger increased GSH Px and reduced LPO in the rats' blood. Ginger could inhibit and/or scaveng radicals of rat body in different degrees.

关 键 词：生姜 高血脂 大鼠 脂质过氧化 研究 

分 类 号：R589.2[医药卫生—内分泌] R285.5[医药卫生—内科学]