非甾体类药物致消化道溃疡病及急性胃肠粘膜病变60例内镜特征分析  

Analysis endoscopic expression of 60 cases of gastrointestinal ulcer and acute mucosal disease by nonsteroidal anti-inflammatory drugs

作　　者：周稻菽[1] 王海波[1] 赵逵[1] 熊弦[1] 刘模荣[1] 

机构地区：[1]遵义医学院附属医院消化内科,贵州遵义563003

出　　处：《遵义医学院学报》2002年第6期515-516,共2页Journal of Zunyi Medical University

摘　　要：目的　探讨非甾体类药物 (NSAID)致消化道溃疡病及急性胃肠粘膜病变的内镜特点及影响因素。方法　回顾分析我院近 2 0 0 1年 1月至 2 0 0 2年 9月门诊及住院病人因服用NSAID致消化道溃疡病及急性胃肠粘膜病变的内镜特点、用药种类及服药后发病时间。结果　 6 0例服用NSAID者 ,服药种类多样 ,服药后出现症状的时间从 1d到数十年不等。发生消化性溃疡病 35例 ,其中男性 2 3例 ,女性 12例 ,男∶女 =1.92∶1;发生急性胃肠粘膜病变 2 5例 ,男∶女 =0 .92∶1。结论　NSAID是消化道溃疡病及急性胃肠粘膜病变的重要病因 ,发生消化道溃疡的种类多样 ;雌激素对NSAID诱发的消化道溃疡病可能具有保护作用 ;气候条件也是影响发病的因素之一。Objective To present the endoscopic character of the gastrointestinal ulcer and acute mucosal disease by NSAID and their affection. Methods The endoscopic character, drugs and time onset of 60 cases of gastrointesttial ulcer and acute mucosal disease by NSAID were recorded and analyzed. Results The drugs are varied, the time onset are from 1 day to 10 years.The proportion of men and women is 0.92∶1 in 25 cases of acute gastrointestinal mucosal disease and is 1.92∶1 in gastrointestinal ulcer. Conclusions NSAID is significant affection of the gastrointestinal ulcer and acute mucosal disease,estrin maybe acts a protect role, and climate is a inductive element.[

关 键 词：消化道溃疡病 急性胃肠粘膜病变 非甾体类药物 内镜表现 

分 类 号：R573.1[医药卫生—消化系统]