电脉冲化学治疗仪的研制  

The Development of an Electric Pulse Chemotherapy Apparatus

作　　者：单纯玉[1] 辛欣[2] 王金国[2] 孙辉[2] 

机构地区：[1]中国科学院长春光学精密机械与物理研究所 [2]吉林大学中日联谊医院,吉林长春130031

出　　处：《中国医疗器械杂志》2003年第1期33-34,共2页Chinese Journal of Medical Instrumentation

摘　　要：介绍一种高压电脉冲化学治疗仪的原理和结构。该仪器是通过高压脉冲电场对肿瘤细胞进行穿孔.在细胞膜上产生可恢复的微孔通道,使抗癌药物经该通道进入细胞内,达到治疗目的。该仪器由可编程脉冲发生器、高压可调稳压电源、高压功率开关和保护电路组成。This paper introduces the principle and structure of an eletric pulse chemotherapy apparatus. It takes advantage of the permeabilization of the cell membrane by electic pulses to facilitate the delivery of chemotherapeutic drugs into cells. It mainly consists of a programmable pulse generator, adjustable high voltage regulator, high voltage switch and protection circuits.

关 键 词：电脉冲化学治疗仪 研制 电脉冲 电穿孔 电化疗 癌细胞 

分 类 号：R730.58[医药卫生—肿瘤]