单光子计算机断层扫描对单侧脑梗死早期持续康复治疗后脑功能活动状态研究  

A comparison study of brain SPECT rCBF from early neuro rehabilitation therapy in 8 cases of acute cerebral infarction

作　　者：李刚[1] 胡晖[1] 朱雯霞[1] 付东明[1] 徐晓云[1] 厉启松 谢瑞满[3] 

机构地区：[1]上海同济大学医学院附属东方医院神经内科,上海市200120 [2]山东省沂南县中医院内科,山东省沂南市276317 [3]上海复旦大学附属中山医院老年病科,上海市200032

出　　处：《中国临床康复》2003年第1期26-27,F003,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨脑梗死后早期神经康复治疗对脑单光子计算机断层扫描(SPECT)局部脑血流(rCBF)的影响。方法:比较8例急性单侧脑梗死患者经早期神经康复持续治疗后99mTc—双半胱乙酯SPECTrCBF兴趣区法测定结果,并与患者临床神经功能的转归和磁共振改变相对照。结果:病侧额区、上额区以及健侧额区局部脑血流明显增加,与临床神经功能的转归相一致。结论:脑梗死后早期神经康复治疗可以促使脑功能改善,同时显示脑SPECT显像在动态研究脑功能变化中有一定价值。AIM:To observe the changes of brain function after the early and continuous neuro rehabilitation therapy and to infer the mechanism for the changes. METHODS:Eight patients with acute unilateral cerebral infarction received the early and continuous neuro rehabilitation. Before and after the course, comparison of 99mTc ECD SPECT imaging of the six cases were taken. In each SPECT test, the images were reconstructed in the horizontal long axis plane. Semiquantitative analysis of rCBF in ROI model was used to evaluate the changes.RESULTS:The rBCF of 3 brain areas (frontal and supper frontal in the affected side; frontal in the normal side) was obviously increased.The local brain functions were obviously improved and these changes were corresponding to neurological outcome.CONCLUSION:The mechanism of early and continuous neuro rehabilitation in patients with acute cerebral infarction might be explained and brain SPECT imaging is also a useful method of brain function assessment.

关 键 词：单光子 脑梗死 早期 持续康复 治疗 脑功能 CT 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R493[医药卫生—临床医学]