肝动脉化疗栓塞与无水酒精注射序贯治疗中晚期肝癌  

Treatment of Moderate Advanced Liver Cancer by Transcatheter Arterial Chemoembolization and Percutaneous Absolute Ethanol Injection

作　　者：王永恒[1] 韦杨义[1] 黄秉一[1] 

机构地区：[1]湖南中医学院第一附属医院外科,湖南长沙410007

出　　处：《中国医师杂志》2003年第1期19-20,55,共3页Journal of Chinese Physician

摘　　要：目的　评价肝动脉化疗栓塞 (TOCE)结合经皮无水酒精注射 (APEI)联合治疗中晚期肝癌的临床疗效。方法　回顾分析我院 1993年 5月至 1999年 8月收治的不能一期切除的中晚期肝癌病人 13 7例 ,其中单纯行TOCE 85例 ,TOCE +APEI 5 2例。结果　TPCE +APEI组疗效明显优于单纯TOCE治疗组 ;二期手术切除率 (2 1 15 % )也明显优于单纯TOCE组 (P <0 0 5 ) ;TOCE +APEI组半年 1年、2年、3年生存率分别为 86 5 4%、67 3 1%、43 5 5 %和 2 1 77% ,而TOCE组则分别为 65 89%、77 92 %、2 2 12 %和 1 48% ,两组生存率有显著差异 (P <0 0 5 )。并发症两组无显著差异。结论　TOCE +APEI治疗中晚期肝癌 ,可提高疗效 ,增加二期手术切除机会 。Objective To evaluate the clinical efficacy of transcatheter arterial chemoembolization (TOCE) and percutaneous absolute ethanol injection (APEI) in moderate or advanced liver cancer.Method During May,1993～Aug,1999, 137 patients with unresectable advanced liver cancer were retrospectively studied. 85 cases only received TOCE, 52 cases were treated by TOCE+APEI by B-US guidance.Results The effect in TOCE+APEI group was significant better than that in only TOCE group,the half year, 1-year,2-year and 3-year survival rates of the TOCE+APEI group were 86 54%,67 31%,43 55% and 21 77%,while those of the TOCE group were 65 89%,47 92%,22 12% and 1 48% respectively. There was significant difference between the two groups in survival rate(P<0 05)and complications. Conclusion Advanced liver cancer treated with TOCE+PEI is a good method, which can improve the clinical efficacy , enhance the resectable chances, and could prolongate survival period.

关 键 词：治疗 晚期 肝癌 肝动脉化疗栓塞 无水酒精注射 中期 

分 类 号：R735.7[医药卫生—肿瘤]