人群癫痫危险因素及社会心理因素病例对照研究  

A case-control study on the risk factors and other socio-psychological factors of epilepsy

作　　者：曾军[1] 洪震[1] 黄茂盛[1] 金美华[1] 

机构地区：[1]复旦大学附属华山医院神经病学研究所生物统计与流行病研究室,上海200040

出　　处：《中华流行病学杂志》2003年第2期116-118,共3页Chinese Journal of Epidemiology

摘　　要：目的　了解自然人群癫痫患者的危险因素及社会心理状况。方法　对上海市金山区朱泾镇普查出的 71例原发性癫痫患者 1∶1配对进行危险因素调查及对包括 1 0例继发性在内的癫痫患者进行配对的社会心理状况的问卷调查。结果　经过多因素逐步条件logistic回归分析发现 ,新生儿疾病 (OR =6 .51 7)、饮酒 (OR =1 0 .761 )、癫痫家族史 (OR =5 .41 4 )与癫痫有着很强的关联。病例组的社会心理状况与正常对照组存在着明显的差异 ,在≥ 1 7岁的成人患者中尤其明显。结论　新生儿疾病及产伤、饮酒、癫痫家族史是癫痫发病的危险因素 ,心理与精神异常在癫痫患者中发生率很高。Objective To identify the risk factors and socio psychological condition of epilepsy in general population. Methods A community based, pair matched case control study using the epileptic patients living in Zhujing town, Jinshan district, Shanghai was carried out. Patients were matched for age (±1 years) and gender to controls (81 cases and 81 controls). Data was analyzed with multiple conditional logistic regression. Results As a result of multiple logistic regression, postnatal insults ( OR = 6.517 ), alcohol intake ( OR = 10.761 ) and family history ( OR = 5.414 ) were powerfully associated with epilepsy. Compared with control group, epileptic patients were significantly different in socio psychological condition, especially in ≥17 years adult patients. Conclusion Postnatal insults, alcohol intake and family history were the risk factors of epilepsy. Psychological and psychiatric disorders were highly prevalent among epilepsy patients.

关 键 词：癫痫 危险因素 社会心理因素 病例对照研究 

分 类 号：R742.1[医药卫生—神经病学与精神病学]