造血干细胞移植后合并疱疹病毒感染的临床分析  

The clinial analysis of herpesvirus infection in hematopoietic stem cell transplantation

作　　者：蔡正文[1] 赖永榕[1] 刘汉锋[1] 牛威林[1] 卢玉英[1] 邓旭[1] 

机构地区：[1]广西医科大学第一附院血液科,530021

出　　处：《广西医学》2003年第2期173-175,共3页Guangxi Medical Journal

摘　　要：目的 :探讨造血干细胞移植 (HSCT)合并疱疹病毒感染的预防和治疗方法。方法 :对 2 1例 HSCT的临床资料进行回顾性分析。疱疹病毒感染的预防 :给予无环鸟苷 5 0 0 m g/ d,从 0天～ +2 8天静脉滴注预防病毒感染。疱疹病毒感染的治疗 :采用无环鸟苷、α-干扰素和丙种球蛋白联合方案治疗。结果 :2 1例患者移植后合并疱疹病毒感染 5例 (发生率 2 3.8% ) ,经过上述治疗后 ,5例疱疹病毒感染患者全部治愈 ,无一例因疱疹病毒感染死亡。结论 :应用无环鸟苷可推迟疱疹病毒感染的发生但不能阻断其发病 ,无环鸟苷、Objective:To explore the prophylaxis and treatment of herpesvirus infection in hematopoietic stem cell transplantation(HSCT) Methods:The data of 21 HSCT patients were reviewed.Aciclovir was given prophylactically to all patients at a dose of 500mg/d from day 0 to day +28.Herpesvirus infection was treated by simultaneous application of aciclovir,IFN α and human immunoglobulin Results:Herpesvirus infection occurred in 5 cases(23 8%).No patients died of complications associated with herpesvirus infection Conclusion:A combination of aciclovir,IFN α and human immunoglobulin is effective for the treatment of herpesvirus infection in HSCT

关 键 词：临床分析 造血干细胞移植 疱疹病毒 白血病 

分 类 号：R733.7[医药卫生—肿瘤]