含二茂铁基的咪唑啉酮类化合物的合成与生物活性  

Synthesis and Biological Activity of Imidazoline Derivatives Containing Ferrocenyl Moity

作　　者：许志锋[1] 丁明武[2] 

机构地区：[1]衡阳师范学院化学系,衡阳421008 [2]华中师范大学有机合成研究所

出　　处：《应用化学》2003年第2期178-180,共3页Chinese Journal of Applied Chemistry

基　　金：湖南省普通高校青年骨干教师培养经费资助项目;衡阳师范学院科学基金启动项目 ( 2 0 0 0D0 4)

摘　　要：The easily accesible azidoethylacetate 1 was reacted with ferrocene formaldehyde to give azide 2, which was allowed to take Staudinger reactions with triphenylphosphine to give iminophosphorane 3. The imidazolinone derivatives containing ferrocenyl moity(5a～5e) were synthesized by a tandem aza-Wittig reaction of 3 with phenyl isocynate and substituted phenols in yields of 57%～69%. The structures of title compounds were confirmed by elemental analysis,IR and 1H NMR. Two of them 5b and 5c exhibited fungicidal activities and none of them has herbicidal activity and insecticidal activity.The easily accesible azidoethylacetate 1 was reacted with ferrocene formaldehyde to give azide 2, which was allowed to take Staudinger reactions with triphenylphosphine to give iminophosphorane 3. The imidazolinone derivatives containing ferrocenyl moity(5a～5e) were synthesized by a tandem aza-Wittig reaction of 3 with phenyl isocynate and substituted phenols in yields of 57%～69%. The structures of title compounds were confirmed by elemental analysis,IR and 1H NMR. Two of them 5b and 5c exhibited fungicidal activities and none of them has herbicidal activity and insecticidal activity.

关 键 词：二茂铁基 嘛唑啉酮 合成 AZA-WITTIG反应 生物活性 除草剂 

分 类 号：TQ457.29[化学工程—农药化工]