成人脑静脉系统血栓形成病因及治疗初探  

A Study of etiology and treatment of cerebral venous system thrombosis.

作　　者：王会刚[1] 周卫东[2] 王得新[1] 贾健平[2] 袁丽品 

机构地区：[1]首都医科大学附属北京友谊医院神经内科,北京100050 [2]首都医科大学附属宣武医院神经内科 [3]河南省汝州市第一人民医院内科

出　　处：《中国神经精神疾病杂志》2003年第1期7-9,共3页Chinese Journal of Nervous and Mental Diseases

摘　　要：目的 研究脑静脉系统血栓形成(CVST)的病因及治疗。方法 对1985年1月至2001年12月经血管造影、手术、DSA与MRA综合确诊的CVST病人86例进行临床分析。结果 未发现明确病因者40例,发现可能病因者46例:其中围产期9例,感冒史8例,偏头痛8例,高血压伴血脂异常8例,口服避孕药6例,外伤手术3例,溃疡性结肠炎2例,单纯缺血性贫血1例,白塞氏病1例。经抗凝、溶栓治疗,痊愈35例,显效18例,好转24例,死亡5例,自动出院4例。结论 CVST可能的病因出现多样化;溃疡性结肠炎及孕高症延误治疗会导致CVST,应引起注意。治疗以抗凝和静脉内溶栓为主,抗凝治疗有效且相对安全;溶栓药物和剂量还需进一步探讨。Objective To investigate the etiology and treatment of Cerebral venous system thrombosis. Methods 86 cases of cerebal venous system thrombosis were proved by angiography or MRA. Their age ranged from 13 to 59(Mean age 32.5) , male 39, female 47.Results 46 of the patients (53.5%) had possible etiological events: peripartum and postpartum (9/86), com-mom cold (8/86), migrain (8/86), hyperlipoidemia (8/86), oral contraception intake (1/86). 40.5% (35/86) of patients gained recovery by thrombolysis, anticoagulation and other therapy. Conclusions The majority of patients with cerebral venous system thrombosis is young people. There was no clear etiological events in approximately half of the patients. The etology of CYST may be varied. Therombolysis and anticoagulation are the main therapy for CVST. Low molecular weight heparin anticoagulation is safety relatively. A randomized, prospective study comparing these two treatment for CVST is warranted.

关 键 词：成人 脑静脉系统血栓形成 病因 治疗 

分 类 号：R743[医药卫生—神经病学与精神病学]