γ-氨基丁酸茶(Gabaron Tea)降血压机理的研究  

Study on the Functional Mechanism of Gabaron Tea on Hypertension

作　　者：林智[1] 大森正司 

机构地区：[1]农业部茶叶化学工程重点开放实验室 [2]日本大妻女子大学

出　　处：《茶叶科学》2001年第2期153-156,136,共5页Journal of Tea Science

摘　　要：采用14 C放射性自显影和化学定量法研究γ -氨基丁酸在白鼠体内的吸收和代谢。结果表明 ,对 6～ 7周Wister雄性白鼠灌胃γ -氨基丁酸 1mg/g体重 ,1小时后 ,肝脏中γ -氨基丁酸的浓度达到最高值 ,3小时后血液和肾脏中γ -氨基丁酸的浓度达到最高值 ,脑中γ -氨基丁酸的浓度变化不大。γThe absorption and metabolism of γ-aminobutyric acid(GABA) in rat were investigated by using 14 C autoradiograph and quantitative analysis method. The results showed that after administrated with 1mg/g body weight GABA to the 6～7 weeks old Wister rats, GABA in the liver increased to the highest level after 1 hour, GABA in the plasm and kidney reached the highest level after 3 hours, while GABA in the brain almost remained at the same level. γ- hydroxybutyric acid(GHBA) was one of the major metabolic products of GABA in rat.

关 键 词：Γ-氨基丁酸茶 GabaronTea 降血压机理 Γ-氨基丁酸 代谢 Γ-羟基丁酸 

分 类 号：R285.6[医药卫生—中药学]