Nafion聚合物涂层碳纤维微电极微分脉冲伏安法测定咖啡因的研究  

Determination of Caffeine by Differential Pulse Voltammetry with Nafion Coating Carbon Fibre Electrode

作　　者：孙长清[1] 高蒨 许宏鼎[1] 郭黎平[2] 

机构地区：[1]吉林大学化学系,长春130023 [2]东北师范大学化学系

出　　处：《高等学校化学学报》1992年第11期1380-1382,共3页Chemical Journal of Chinese Universities

基　　金：中国科学院长春应用化学研究所电分折化学开放实验室资助

摘　　要：<正> 咖啡因属生物碱,是中枢神经兴奋药物之一~[1]。目前,咖啡因的常用测定方法有紫外分光光度法~[2]和高效液相色谱法~[3]等.电化学测定方法已有报道~[4～6],但尚未见到利用Nafion聚合物涂层碳纤维微电极的伏安测定方法.本文提出了一种简单易行的碳纤维微电极及其Nafion聚合物涂层的制造方法.A Nafion modified carbon fibre microelectrode was established.The response of caffeine at the Nafion coating microelectrode was evaluated by differential pulse voltammetry.The linear relationship between the peak height and the concentration of caffeine in the range of 2×10-5~5×10-4mol/L is obtained.By means of cyclic voltammetry the kinetic behaviour of caffeine on the electrode was studied.This method was also applied to the direct determination of caffeine in drugs.

关 键 词：碳纤维 微电极 咖啡因 伏安法 

分 类 号：R971.7[医药卫生—药品]