血清CA19-9水平与胰腺癌转移及手术切除率关系的初步探讨  

THE RELATIONSHIP BETWEEN SERUM CA19-9 LEVEL AND METASTASIS AND RESECTION RATE OF PANCREATIC CARCINOMA

作　　者：宗明[1] 汤朝晖[1] 傅晓辉[1] 王本茂[1] 吴孟超[1] 

机构地区：[1]第二军医大学附属东方肝胆外科医院,上海200438

出　　处：《肝胆外科杂志》2003年第1期27-29,共3页Journal of Hepatobiliary Surgery

摘　　要：目的　探讨血清 CA19- 9水平与胰腺癌病程的关系。方法　测定 5 0例病理检查确诊的胰腺癌血清 CA19- 9水平 ,分析 CA19- 9水平与胰腺癌有无远处转移、血管侵犯及手术切除率的关系。结果　高血清 CA19- 9水平 (>2 0 0 U/ ml)组合并远处转移率 (14例 ,5 6 % )明显高于低血清 CA19- 9水平组 (5例 ,2 0 % ) (P<0 .0 1) ,而合并血管受侵率 (14例 ,5 6 % )与低血清 CA19- 9水平组 (9例 ,36 % )相比差异不大 (P>0 .0 5 )。高血清 CA19- 9水平组患者的根治性肿瘤切除率 (3例 ,12 % )明显低于低血清 CA19- 9水平组 (11例 ,4 4 % ) (P<0 .0 1)。结论　血清 CA19-Objective To study the relationship between serum CA19 9 level and metastasis rate,resection rate of pancreatic carcinoma.Methods 50 patients with pancreatic carcinoma were divided into high serum CA19 9 level (>200 U/ml) group and hypo serum CA19 9 level (≤200 U/ml) group.The relationships between serum CA19 9 level and metastasis rate,resective rate of pancreatic carcinoma were analysed.Results Compared with 25 patients with hypo serum CA19-9 level (≤200 U/ml) group,metastasis rate or pancreatic carcinoma is higher significantly (14/5 cases,P<0.01),and resective rate is lower significantly(3/11 cases, P<0.01) in 25 patients with high serum CA19 9 level (>200 U/ml)group.Conclusion Serum CA19 9 level may be of important value in predicton of metastasis of pancreatic carcinoma.

关 键 词：胰腺癌 CA19-9 转移 手术切除 

分 类 号：R735.9[医药卫生—肿瘤]