介入化疗栓塞治疗鼻咽癌的临床价值  

Clinical Value of Transcatheter Arterial Chemotherapy Embolism in Nasopharyngeal Carcinoma Patients

作　　者：陈锦生[1] 文锡荣[1] 郑佳坤[1] 詹永忠[1] 陈成武[1] 许玩兰[1] 李奕如[1] 陈胜润[1] 林介仁[1] 张敏[1] 

机构地区：[1]潮州市中心医院,广东潮州521021

出　　处：《肿瘤防治杂志》2003年第1期71-73,共3页China Journal of Cancer Prevention and Treatment

基　　金：广东省卫生系统"五个一工程"重点专科基金资助(96186)

摘　　要：目的:探讨介入动脉化疗栓塞治疗鼻咽癌的临床价值。方法:将87例鼻咽癌患者分成3组:1)A组(介入化疗+放疗组)26例;2)B组(放疗+化疗组)29例;3)C组(单纯放疗组)32例。结果:随访48-61个月,近期疗效CR分别为A组80.8％、B组58.6％、C组50.0％,A组与B、c组分别比较,差异均有显著性(P<0.05);2、3、4年生存率分别为:A组80.8％、76.9％、61.5％,B组58.6％、51.7％、44.8％,C组46.9％、40.6％、37.5％。结论:采用放疗结合介入化疗栓塞对鼻咽癌治疗有协同作用,值得临床推广应用。Objective To explore the value of transcatheter arterial chemoembolization (TACE) for nasopharyngeal carcinoma. Methods Eighty-seven cases of nasopharyngeal carcinoma were divided randomized into third groumps:l)A group (transcatheter arterial chemoembolization and radiotherapy), 26 cases.2)B group (radiotherapy and chemotherapy ) ,29 cases.3)C group (simple radiotherapy) ,32 cases. Resi;ts All patients were followed up for 48-61 months.The rates of immediate complete response (CR) of A group,B group and C group were 80.8% and 58.6% and 50.0% respectively (P < 0.05).The A group showed higher 2-,3- and 4-year survival rates than B group and C group with 80.8% ,76.9% ,61.5% and 58.6% , 51.7% ,44.8% and 46.9%,40.6%, 37.5%,respectively (P < 0.01) .Conclusions Radiotherapy plus transcatheter arterial chemotherapy embolism simultaneously for nasopharyngeal carcinoma has synergetic effect, and it needs to be further discussed.

关 键 词：鼻咽肿瘤 放射疗法 药物疗法 治疗性化学栓塞 

分 类 号：R739.63[医药卫生—肿瘤] R730.53[医药卫生—临床医学]