麻痹性痴呆4例临床分析  

Clinical analysis of 4 cases with general Paralysis of insane

作　　者：陈海峰[1] 戴彩华[2] 陈海波[1] 吴文艳[1] 

机构地区：[1]吉安市第三人民医院,江西吉安343000 [2]井冈山大学医学院,江西吉安343000

出　　处：《井冈山大学学报（自然科学版）》2009年第5期104-105,共2页Journal of Jinggangshan University (Natural Science)

摘　　要：目的分析麻痹性痴呆的临床特征和诊断。方法回顾性分析4例麻痹性痴呆患者的临床资料,智能测定和各项实验室检查结果。结果4例患者误诊为精神分裂症3例。4例患者血清梅毒抗体检查均为阳性,2例脑脊液梅毒抗体阳性,简易智力状况检查评分均≤21分。经青霉素和抗精神药物治疗后,一般精神症状控制,但均有不同程度的智能下降。结论麻痹性痴呆极易误诊,临床表现、梅毒血清学、脑脊液检查是诊断的重要依据,早期诊断和治疗是预后的关键。Objective:To analyze the clinical features and diagnostic methods of general paralysis of insane(GPI).Methods: Clinical data of 4 GPI cases were retrospectively analyzed.Results: Among 4 cases,3 were given wrong diagnosis of Schizophrenia,The blood tests for syphilis of 4 cases were positive as well as from the cerebrospinal fluid(CSF) of 2 cases.The scores of Mini Mental State Examination(MMSE) were ≤21.After treatment by antispyhilitic and antipsychotics,Clinical symptoms were controlled and there were different degree decrease of intelligence.Conclusion: GPI is very easily misdiagnose.Important basis of di-agnosis remains on clinical manifestations,test of syphilis antibody and examination of CSF.Early finding and intervention might be the key for prognosis.

关 键 词：麻痹性痴呆 误诊 梅毒抗体检查 

分 类 号：R749.1[医药卫生—神经病学与精神病学]