SPECT脑血流显像在难治性癫癎灶定位诊断中的价值  

Value of Cerebral Blood Flow Imaging of Single Photon Emission Computed Tomography in Localization Diagnosis of Intractable Epilepsy

作　　者：张遵城[1] 李小东[1] 董萍[1] 肖连冬[1] 王钦[1] 

机构地区：[1]天津医科大学第二医院核医学科,300211

出　　处：《天津医药》2003年第3期151-153,共3页Tianjin Medical Journal

摘　　要：目的 :探讨单光子发射计算机断层(SPECT)脑血流显像在癫灶定位诊断 ,指导癫外科治疗的价值。方法 :对88例难治性癫患者进行了脑电图(EEG) ,磁共振成像(MRI)和SPECT脑血流显像检查 ,其中42例患者进行了外科(开颅手术或γ刀放射)治疗。结果 :SPECT脑血流显像的阳性率最高 ,为90.9 % ,EEG和MRI的阳性率分别为76.1 %和40.9 %。外科治疗患者SPECT与EEG定位结果的一致及相对一致率为83.3 % ,SPECT与MRI定位结果的一致及相对一致率为81.3 %。3者定位结果的一致及相对一致率为75.0 %。外科治疗的有效率为83.3 %。结论 :SPECT脑血流显像是诊断癫灶灵敏而有效的方法 。Objective:To investigate the value of cerebral blood flow imaging of single photon emission comˉputed tomography(SPECT)in localization diagnosis of intractable epilepsy.Methods:EEG,MRI and SPECT cerebral blood flow imaging were carried in88patients with medically intractable epilepsy,among them42patients underwent either open skull operation orγknife surgical therapy according to the results of examinaˉtion.Results:The highest positive rate(90.9%)was found in SPECT.The positive rates of EEG and MRI were76.1%and40.9%.In patients treated by surgery,the localization of epileptic focus by SPECT was in complete or relative concordance with EEG in83.3%patients,with MRI in81.3%patients,with both of them in75.0%patients.Conclusion:The SPECT cerebral blood flow imaging is a sensitive and effective method in detecting and localizing epileptic fici and is useful in rightly choosing surgical scheme to obtain good curative effect.

关 键 词：SPECT 脑血流显像 难治性癫痫 定位诊断 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R816.1[医药卫生—临床医学]