^(125)I粒子永久性植入组织间治疗胰腺癌的临床报告  

Clinical application on iodine-125 seeds interstitial brachytherapy for the cancer of pancreas

作　　者：杨国凯[1] 罗开元[1] 杨镛[1] 杨嵘[1] 王明春[1] 毛文源[1] 邵庆华[1] 刘文卓[1] 

机构地区：[1]云南省第二人民医院普外科,昆明650021

出　　处：《临床外科杂志》2003年第2期92-93,共2页Journal of Clinical Surgery

摘　　要：目的　探讨　12 5I永久性植入组织间治疗不能切除的胰腺癌的疗效。方法　选择晚期胰腺癌病人 12例。将12 5I粒子永久性植入癌组织区域和癌细胞转移途径的各组 (站 )淋巴结区域。术后 3～ 7d测血象及免疫指标 ,1周后摄X片观察12 5I分布状况 ,观察有效率。结果　有效率41.67% ,病人的平均生存时间为 9.66个月 ,其中 1例已经存活 2 5个月 ,无一例出现因植入12 5I粒子而导致的严重并发症。结论　组织间永久性植入12 5I粒子治疗恶性肿瘤方法简单、安全。Objective To explore the clinical effects of 125 I seeds interstitial brachytherapy in treatment of the cancer of pancreas.Methods 12 patients with pancreatic cancer underwent performed using 125 I intraoperative permanent implantation to tumor bed and regional lymph nodes.Postoperative 3～7 days WBC count and immuoassay were detected after one week,film X-ray was taken to observe the distribution of 125 I seeds.Result 12 patients average survived 9.66-month,and one survive 25-months.No patient present severes complications .Conclusions 125 I seeds interstitialbrachytherapy for the malignant tumor of pancreas is simple,safe and effective,and it is one of ideal methods to treat cancer.

关 键 词：组织间放疗 ^125I粒子 胰腺癌 

分 类 号：R735.9[医药卫生—肿瘤]