Eph受体和Ephrin配体的研究进展  

Recent advances in Eph receptors and Ephrin ligands

作　　者：罗超[1] 田刚[1] 许民辉[1] 

机构地区：[1]第三军医大学附属大坪医院神经外科,重庆,400042

出　　处：《中国癌症杂志》2003年第1期79-82,共4页China Oncology

摘　　要：蛋白酪氨酸激酶基因家族是最大的癌基因家族 ,蛋白酪氨酸激酶参与信号传导通路、控制细胞形态、参与细胞增殖、分化和迁移。Protein tyrosine kinase genes are the largest family of oncogenes. This is not surprising since protein tyrosine kinases are important components of signal transduction pathways that control cell shapes, proliferation, differentiation, and migration. This review will address the recent progress in understanding the function of Eph receptor and ephrin ligands in normal development and how disregulation of these functions could promote tumorigenesis.

关 键 词：受体酪氨酸激酶 轴突向导 血管生成 

分 类 号：R730.23[医药卫生—肿瘤]