心力衰竭患儿血清脂质过氧化物含量的变化  

CHANGES OF LIPID PEROXIDE IN CHILDREN WITH HEART FAILURE

作　　者：黄伟民[1] 龙盛京[2] 李雪华[2] 覃爱娟[2] 李德勇[2] 李毅[2] 

机构地区：[1]广西医学院儿科教研室 [2]广西医学院化学教研室

出　　处：《广西医学院学报》1992年第4期38-40,共3页

基　　金：国家自然科学基金

摘　　要：测定20例心力衰竭患儿血清脂质过氧化物(LPO)含量,结果显示,心衰患儿血清LPO含量(4.64±2.19μmol/L)显著高于正常组(2.77±0.56μmol/L)及心脏病无心衰组(2.84±0.88μmol/L),Ⅲ°心衰组(5.80±2.89μmol/L)高于Ⅱ°心衰组(3.54±0.66μmol/L).提示氧自由基引发的脂质过氧化损伤在心力衰竭发生、发展的病理过程中起一定作用.Serum lipid peroxides(LPO)were measured in twenty children with heart failure.The mean value of LPO was 4.64±2.19μmol/L in the heart failure group, which was significantly higher than that of the normal group(2.77±0.55μmol/L)and that of the heart diseases without heart failure group(2.84±0.88μmol/L).The mean value of the Ⅲ degree heart failure group(5.80±2.89μmol/L)was higher than that of the Ⅱ degree heart failure group (3.54±0.66μmol/L).These results suggest.that oxygen free radicals may play a role in the pathological process of heart failure.

关 键 词：心力衰竭 氧自由基 过氧化脂质 

分 类 号：R725.416[医药卫生—儿科]