^(125)I粒子组织间永久植入治疗恶性肿瘤(附113例分析)  

Malignant tumor treated by radioactive ^(125)I particle permanently implanted in tissue:A report of 113 cases

作　　者：叶有生[1] 孙永安[1] 曹培[1] 宁占河[1] 王平[1] 蔡利[1] 霍云霞[1] 郑月[1] 李燕[1] 于世平[2] 

机构地区：[1]沈阳军区总院分院外科,沈阳110031 [2]北京医科大学附一院放射治疗科,北京100034

出　　处：《第二军医大学学报》2003年第3期347-348,共2页Academic Journal of Second Military Medical University

摘　　要：为观察12 5I放射粒子组织间永久性植入治疗恶性肿瘤的临床效果 ,选择 113例的治疗病例 ,其中口腔、颌面部肿瘤 4 9例 ,头、肺、乳腺、肝、胰、结肠、直肠及前列腺等各种肿瘤共 6 4例 ,病理诊断明确。经CT定位术植入 5 7例 ,CT、B超引导下经皮穿刺植入 5 2例 ,模板插植 3例 ,立体定向支架术插植 1例 ,均为组织间永久植入。随访 4 10个月 ,结果显示有 2例患者肿瘤完全消失 ,4例晚期肿瘤患者 6个月后转移衰竭死亡 ,2例因心脑疾病死亡 ,其余患者肿瘤均有不同程度缩小 ,症状改善 ,生存时间延长。在治疗中 ,全组无白细胞下降 ,无因植入12 5I粒子而导致的严重并发症。临床实践证明12 5I放射粒子组织间永久植入治疗恶性肿瘤安全有效 。In this study 125 I radioactive particle was permanently implanted in tissues to treat malignant tumor in 113 patients, in which 49 cases had oral and maxillofacial tumors, 64 cases had head, lung, mammary gland, liver, pancreas, colon, rectum, and prostate tumors. Fifty seven cases implantation were guided by CT location, 52 cases of percutaneous puncture by CT and ultrasound scanner type B. There were 3 cases template insertion implantation, 1 case three dimensional, orientation cytoskeletal insertion implantation. Tumors disappeared completely in 2 patients, there were 4 late tumor patients died of transfer failure after 6 months, 2 cases died of cardio cerebral disease. The tumors in remaining cases all shrank to different degree with longer survival time. There was no reduce of white blood cells or severe complication. Treating malignant tumor by implanting 125 I radioactive particle in tissues permanently is safe and effective.

关 键 词：^125I粒子 组织间永久植入 恶性肿瘤 

分 类 号：R730.53[医药卫生—肿瘤]