针灸对Ⅰ型变态反应患者嗜碱细胞脱颗粒试验(HBDT)的影响  

Acupuncture Effect on Human Basophilic Degranulation Test in Allergy Type I

作　　者：赖新生[1] 司徒铃[1] 靳瑞[1] 张家维[1] 贺紫兰[2] 赖乃揆[2] 熊慰阳[2] 陈小右[2] 

机构地区：[1]广州中医学院针灸系 [2]广州医学院第二附院变态科

出　　处：《广州中医学院学报》1992年第1期52-55,共4页

摘　　要：本文以HBDT为指标,观察针刺对致敏细胞敏感性的调节效应。实验表明:针灸组与脱敏组治疗前螨抗原HBDT最大脱颗粒指数均大于30％而达到50％以上,治疗后以针灸组下降较明显,组间比较差异有显著意义(P<0.05),针灸组变应性哮喘患者的蟑螂抗原HBDT最大脱颗粒指数治前为56.9±16.42(％),治后下降至22.88±24.53(％),自身前后对比差异有显著意义(P<0.05)。提示针灸可抑制过敏状态下的嗜碱细胞脱颗粒,可能通过调整作用稳定致敏细胞,在细胞级水平上达到抗变态反应的直接作用。In this study the acupuncture regulatory effect on the sensitivity of the sernsitized cells was observed by using human basophilic degranulation test (HBDT). The experimental results showed that before treatment in both the acupuncture and desensitization groups the degranulation indexes were over 30％ to over 50％. But after treatment the index of acupuncture group decreased markedly. Compared with that of the desensitigation group, the difference was grently significant(P<0.05). And in the acupuncture group, the maximum degranulation index induced by cockroach antigen in the cases with allergic asthma decreased form 56.9±16.42％ to 22.88±24.55％, and the difference before and after treatment was significant(P<0.05). This indicated that acupuncture could stabilize the sensitized cells and might change the quality and quantity of basophilic cell.

关 键 词：哮喘 针炙疗法 嗜碱细胞 

分 类 号：R246.1[医药卫生—针灸推拿学]